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Tag: Cholesterol

April 14, 2023 CD as API / CD derivatives / Pharma applications

Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing

Core–shell superparamagnetic iron oxide nanoparticles hold great promise as a theranostic platform in biological systems. Herein, we report the biological

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March 17, 2023 Life sciences

Methyl BCD alters cell envelop studied by AFM

To elucidate the involvement of the cell envelope in the stiffness of sickle cells, methyl-β-cyclodextrin (MβCD), a putative cholesterol-depleting reagent

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March 16, 2023 CD as API / CD derivatives / Life sciences / Pharma applications

Patent application: gamma-cyclodextrin-based polymer for prevention or treatment of cholesterol metabolism-related diseases

RENATUS, a South Korea-based pharma company pioneering next generation cyclodextrin-based therapies for the safe treatment of cholesterol-associated diseases recently filed

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March 3, 2023 CD as API / Pharma applications

Veklury® (remdesivir) formulations inhibit initial membrane-coupled events of SARS-CoV-2 infection due to their sulfobutylether-β-cyclodextrin content

Background and purpose: Despite its contradictory clinical performance, Veklury® (remdesivir) has a pivotal role in COVID-19 therapy. Possible contributions of the

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February 28, 2023 CD as API / Pharma applications / Uncategorized

Dimethyl-α-cyclodextrin induces capacitation by removing phospholipids from the plasma membrane of mouse sperm

Dimethyl-alpha-CD (DMACD) was found to enhance sperm fertilization ability by removing phospholipids. It was concluded that in addition to the

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February 3, 2023 CD as API / CD derivatives / Pharma applications

Mannose-modified methyl-β-cyclodextrin suppresses tumor growth

Methylated β-cyclodextrin (MeβCD) can extract cholesterol from lipid rafts and induce apoptosis in cancer cells by inhibiting activation of the

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December 23, 2022 Food / Non-pharma applications / Uncategorized

Can CDs be utilized in/for Christmas turkey?

There many ways for applying CDs for the preparation of the traditional roasted turkey for Christmas. The method of spraying

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December 1, 2022 CD as API / Pharma applications

Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

In this review, based on 250 references, the general chemical principles of direct cyclodextrin–protein interactions are summarized and highlighted, through

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October 25, 2022 CD as API / Pharma applications

Australian company pioneering Cavadextrin for regression of atherosclerosis

Newsmaker, the Australian Press Release Distribution Service has published the news on “An Australian pioneering a medical breakthrough treatment that

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October 11, 2022 CD as API / Pharma applications

Inclusion Solves Insolubility ―Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C

Cyclodextrins (CDs) are used not only as pharmaceutical excipients but also as active pharmaceutical ingredients. CDs can act as artificial

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Recent Posts

  • New book on cyclodextrin glucanotransferase
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Innovative Titanium Coatings for Enhanced Dental Implants
  • Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers
  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng

Tags

alpha-CD atherosclerosis Cancer therapy Captisol Cholesterol Clinical trial conference Covid-19 cyclodextrin polymer Dexolve drug delivery drug delivery systems electrospinning FDA Food gamma-CD Gilead HPBCD hydrogel methyl BCD Nanoparticles Niemann Pick Disease RAMEB remdesivir review SBECD Special issue Sugammadex Synthesis

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Top Posts

  • New book on cyclodextrin glucanotransferase
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Lanosterol eye drops for cataract treatment
  • Multiple therapeutic benefits of Sulforaphane/alpha-cyclodextrin complex
  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng
  • Toruzyme® for synthesizing cyclodextrins from starch
  • Effects of water matrix constituents on micropollutant removal by activated carbon and b-cyclodextrin polymer adsorbents
  • Gamma cyclodextrin / Theanine chewable developed for anxious pets
  • Advances in cyclodextrin-based materials: Anticancer and antimicrobial applications–A review (2021–2024)
  • Comparative study of thiolated and alkenylated functionalized β-CDs as highly mucopenetrating and mucoadhesive drug delivery systems.

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