A forum for researchers, students and applicants in the field of cyclodextrin technology
A promising therapy for atherosclerosis treatment was designed by targeting LXR receptor (LXR) on atherosclerotic macrophage, where LXR activation could
Niemann-Pick type C is a sever lysosomal storage disease, commonly refereed as ‘children’s Alzheimer’. There is no cure for it
In this work, it is demonstrated that liposome active motion takes advantage of mainly a pair of intrinsic material properties
In this recently published article, the effect of four cyclodextrin derivatives on cholesterol and ganglioside depletion was investigated: two alpha
HP-beta-cyclodextrin (HPbCD) is currently in clinical trials against Niemann-Pick Disease Type C (NPC) and Alzheimer’s Disease (AD) and these trials
The application of cyclodextrins in food technology is extensive due to their unique ability to form complexes with many bioactive
Atherosclerosis is a major cause of mortality and morbidity worldwide. Left undiagnosed and untreated, atherosclerotic plaques can rupture and cause
Sensitive and rapid monitoring of cholesterol levels in the human body are highly desirable as they are directly related to
Nanoparticle-based therapeutics represent potential strategies for treating atherosclerosis; however, the complex plaque microenvironment poses a barrier for nanoparticles to target
Conformational search and density functional theory calculations were performed to find the most stable conformation with the lowest complexation energy
