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Tag: Cholesterol

May 12, 2022 CD as API / Pharma applications

Cothreading of Unmodified and Monoazidated β-Mixed cyclodextrins in polyrotaxanes for Niemann Pick disease

To establish a method for the orthogonal chemical functionalization of β-cyclodextrin (β-CD)-based polyrotaxane (PRX), unmodified and monoazidated β-CDs (N3-β-CDs) were

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March 22, 2022 CD as API / Life sciences / Pharma applications

Methyl BCD against malaria?

The researchers of College of Medicine (Pennsylvania) and Iowa University have published on ‘Dramatic Consequences of Reducing Erythrocyte Membrane Cholesterol

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January 26, 2022 CD as API / CD derivatives / Pharma applications

Poly-β-cyclodextrin Supramolecular Nanoassembly with a pH-Sensitive Switch Removing Lysosomal Cholesterol Crystals for Antiatherosclerosis

Cholesterol crystals (CCs), originally accumulating in the lysosome of cholesterol-laden cells, can aggravate the progression of atherosclerosis. β-cyclodextrin (CD) is

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January 6, 2022 CD as API / Pharma applications

Beta-Cyclodextrin/L-Arginine/Au Nanomotors for Atherosclerosis

Most of the current non-pharmacological treatment strategies for atherosclerosis (AS) suffer from poor penetration into the plaque and only aim

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November 30, 2021 CD derivatives / Life sciences

Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the KV1.3 Ion Channel Independent of Membrane Cholesterol Extraction

Effects of CDs exerted on cellular functions are generally thought to originate from reductions in cholesterol levels. Potential direct, ligand-like

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November 18, 2021 Food / Non-pharma applications

Lecithin Inclusion by α-Cyclodextrin Activates SREBP2 Signaling in the Gut and Ameliorates Postprandial Hyperglycemia

α-cyclodextrin (α-CD) is one of the dietary fibers that may have a beneficial effect on cholesterol and/or glucose metabolism, but

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October 7, 2021 CD as API / Pharma applications

Visualization of cholesterol depletion at the plasma membrane by methyl-β-cyclodextrin

The most common method to modify cellular cholesterol content in vitro is to incubate cells with cyclodextrin (CD). However, it

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September 24, 2021 CD as API / CD derivatives / Events / Pharma applications

Meet the Experts: Cyclodextrins as active ingredients in the 21st century – Webinar of CycloLab

After the great success of the webinar held in May, 2021 a next webinar organized by CycloLab will be held

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September 13, 2021 CD as API / Pharma applications

Think Big, Start Small: How Nanomedicine Could Alleviate the Burden of Rare CNS Diseases

The complexity and organization of the central nervous system (CNS) is widely modulated by the presence of the blood–brain barrier

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September 9, 2021 CD as API / CD derivatives / Pharma applications

Underdog Pharmaceuticals Awarded ‘Innovation Passport’ by UK Regulators

Underdog Pharmaceuticals, Inc. (Underdog), a pre-clinical stage pharmaceutical company focusing on the treatment and reversal of age-related diseases, has been

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Recent Posts

  • New book on cyclodextrin glucanotransferase
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Innovative Titanium Coatings for Enhanced Dental Implants
  • Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers
  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng

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Top Posts

  • New book on cyclodextrin glucanotransferase
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Lanosterol eye drops for cataract treatment
  • Multiple therapeutic benefits of Sulforaphane/alpha-cyclodextrin complex
  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng
  • Toruzyme® for synthesizing cyclodextrins from starch
  • Effects of water matrix constituents on micropollutant removal by activated carbon and b-cyclodextrin polymer adsorbents
  • Gamma cyclodextrin / Theanine chewable developed for anxious pets
  • Advances in cyclodextrin-based materials: Anticancer and antimicrobial applications–A review (2021–2024)
  • Comparative study of thiolated and alkenylated functionalized β-CDs as highly mucopenetrating and mucoadhesive drug delivery systems.

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