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Category: Drug delivery

March 18, 2021 CD as API / Drug delivery / Pharma applications

Multicharge beta-cyclodextrin supramolecular assembly for ATP capture and drug release

Water-soluble seven hexylimidazolium modified amphiphilic cyclodextrin (AMCD) selectively combined with ATP to form a stable 1 : 1 inclusion complex

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March 16, 2021 Drug delivery / Pharma applications

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

Drug combination strategies of repurposed drugs offer a number of advantages to monotherapies including the potential to achieve greater efficacy,

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March 15, 2021 CD derivatives / Drug delivery / Pharma applications

Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery

Thiolated β-cyclodextrin (β-CD) has the potential to enhance mucoadhesive and permeation enhancing properties on ocular mucosa. Thiolated β-CD was synthesized via replacement

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March 12, 2021 Drug delivery / Pharma applications

An interesting hypothesis: CD‐sACE2 inclusion compounds to treat COVID‐19

Angiotensin‐converting enzyme 2 (ACE2) has been identified as the main receptors for SARS‐CoV and SARS‐CoV‐2. Soluble ACE2 (sACE2) can bind

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March 4, 2021 Drug delivery / Pharma applications

FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine

As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen

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March 3, 2021 Drug delivery / Pharma applications

Improving Bioavailability & Solubility

Drug Development & delivery published on the virtual 2020 Global Drug Bioavailability Enhancement Summit, which this past December showcased novel

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March 2, 2021 CD derivatives / Drug delivery / Pharma applications

Heptakis(6-amino-6-deoxy)-beta-cyclodextrin stabilizes the synthetic anticoagulant fondaparinux

The intermolecular interactions between the cationic per-6-amino-b-CD with the highly anionic heparin analogue anticoagulant fondaparinux were studied at two different

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March 1, 2021 Drug delivery / Pharma applications

KAZIA LICENSES CANTRIXIL TO OASMIA

Kazia Therapeutics Limited, an Australian oncology-focused biotechnology company, announced that it has entered into an exclusive worldwide license agreement with

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March 1, 2021 Drug delivery / Pharma applications

Aerogels in drug delivery. Review

Aerogels are the lightest processed solid materials on Earth and with the largest empty volume fraction in their structure. Composition

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February 23, 2021 Drug delivery / Pharma applications

New approach in ocular drug delivery: cyclodextrin-containing mucoadhesive eye drop formulations

 In this study, prednisolone-containing ophthalmic formulations were developed with expected optimal permeation without toxic or irritative effects. The toxicity and

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Recent Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • FDA granted accelerated approval to umbralisib / HPBCD tablet

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Top Posts

  • Registration opened for virtual abridged meeting prior to International Cyclodextrin Symposium
  • Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
  • Cyclodextrins in Antiviral Therapeutics and Vaccines
  • Evading Thermodynamic Constraints of Cyclodextrin-Drug Formulations
  • FDA granted accelerated approval to umbralisib / HPBCD tablet
  • The monograph of SBECD is official in the European Pharmacopeia
  • Nasal delivery with beta-cyclodextrin is approved; a short story of Baqsimi
  • How air fresheners work?
  • Host-guest chemistry for the treatment of leishmania
  • Reviews on cyclodextrin-metal-organic frameworks (CD-MOFs) in food applications

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