Category: Drug delivery
Poly-CD-PEG-camptothecin Combined with Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer (Clinical trial)
The authors hypothesized that integrating tumor-targeted topoisomerase I inhibitor delivery with optimized PARP inhibitor scheduling could enable effective combination therapy
Doxycycline release from cyclodextrin oligomer-containing collagen gels
Researchers at Case Western Reserve University incorporated γ-cyclodextrin oligomers into native collagen gels during fibril formation and studied loading/release of
Cyclodextrin-based polymer materials and their applications – A review covering a 20-year period
Cyclodextrins (CDs) have undergone a remarkable evolution over the past three decades, transitioning from classical solubilizing agents to multifunctional platforms
Pressurized hot water to improve complexation
This study introduces an integrated, green solubilization strategy by combining pressurized hot water (PHW) treatment with β-cyclodextrin (βCD) complexation to
Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer’s disease
The co-delivery of rivastigmine hydrogen tartrate (RHT) and asiaticoside (AS) offers a promising strategy for enhancing acetylcholinesterase (AChE) inhibition in
Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems
Porphyrins are powerful photosensitive molecules with useful photophysical and redox properties, making them attractive for therapeutic use. However, they often
Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
Drug delivery using dissolving or biodegradable polymer microneedles has garnered significant interest in drug administration because of their biocompatibility, fast
Nano-Enabled Toxicity of Pharmaceutical Excipients
Nanotechnology has brought revolutionary advances in the pharmaceutical field. Among drug delivery systems, nanocarriers, which enhance the solubility, stability and
Biphasic dissolving microneedles with cyclodextrin inclusion complexes for enhanced delivery of poorly soluble drugs
Dissolving microneedles (DMNs) have been widely investigated for transdermal drug delivery, yet their clinical translation and commercialization remain limited, primarily