Cyclodextrin based dermatological formulations Dermatopharmaceutical and cosmetic application 

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The incorporation of CDs in dermopharmaceutical and cosmetics formulations has received much attention since the late 1970 s by enhancing modulation of the passage through the skin and vectorization into the target site while simultaneously offering a biocompatible delivery system. This paper features the advantages of CDs in dermopharmaceutical and cosmetic applications, such as the improvement of the apparent solubility and the stability of the active ingredients, the possibility of masking unpleasant odors, among others that are be described, emphasizing that these versatile skin active ingredient carriers are strongly promising both in the treatment of skin diseases and in the improvement of cosmetic formulations.

The following diseases are targeted:

  • Psoriasis
  • Acne
  • Dermatitis
  • Microbial skin diseases
  • Wound healing
  • Skin cancer

The following cosmetic applications are discussed:

  • Sunscreen
  • Anti-aging
  • Deodorant and antiperspirant
  • Shampoo
  • Fragrance

Ferreira L, Mascarenhas-Melo F, Rabaça S, Mathur A, Sharma A, Giram PS, Pawar KD, Rahdar A, Raza F, Veiga F, Mazzola PG, Paiva-Santos AC. Cyclodextrin-based dermatological formulations: Dermopharmaceutical and cosmetic applications. Colloids Surf B Biointerfaces. 2023 Jan;221:113012. doi: 10.1016/j.colsurfb.2022.113012. 

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