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Tag: Niemann Pick Disease

March 4, 2019 CD as API / Pharma applications / Supramolecular systems

Novel polyrotaxane for Niemann Pick disease type C treatment

The team of Gerhard Wenz (Saarland University, Germany) has published a novel polyrotaxane: hydroxypropyl-β-cyclodextrin(HPBCD):poly(decamethylenephosphate) which has several advantages over HPBCD

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February 20, 2019 CD as API / CD derivatives

CTD Reports Initial Data for Two Clinical Trials of Trappsol® Cyclo™

CTD Holdings, Inc., a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical

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February 5, 2019 CD as API / Pharma applications

CTD Announces Partnership with United BioSource

CTD Holdings, a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical need,

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January 2, 2019 CD as API / CD derivatives / Cosmetics and toilettry / Drug delivery / Gene delivery / Non-pharma applications / Pharma applications

Cyclodextrin News Year in Review 2018

The CDNews blog was created in July and after a short period of trial it started in September. During this

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November 22, 2018 Drug delivery / Pharma applications

Cyclodextrins involved in clinical trials to start

According to clinicaltrials.gov, currently, there are 14 cyclodextrin-related clinical trials that in the status of i) Not yet recruiting, ii)

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November 13, 2018 CD as API / Pharma applications

HPBCD treatment for Niemann-Pick C: Mallinckrodt communicated results of clinical trial

Mallinckrodt Pharmaceuticals recently revealed findings of their completed registration trial for VTS-270 (Hydroxypropyl Betadex- HPBCD), a development product to treat

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September 22, 2018 CD as API / Pharma applications

Therapeutic potential for cyclodextrin‐based macromolecular systems in NPC

A paper has just come out in Macromolecular Rapid Communications highlighting the potential benefits of cyclodextrin-based macromolecular systems as cholesterol-mopping

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September 13, 2018 CD as API / Pharma applications

HPBCD was tested for revealing the symptoms of Cockayne syndrome in mouse model: a surprise

Cockayne syndrome is a hereditary form of premature aging caused by a gene mutation. The disease affects more organs including

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August 30, 2018 CD as API / Pharma applications

Different cyclodextrins to treat NPC

If you are following advances in the re-discovery of cyclodextrins as APIs, there is quite a race among the candidates

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August 23, 2018 CD as API / Pharma applications

Advancements of CD analysis in Niemann-Pick C

Clearly, understanding the mechanism of action for cyclodextrins and consequently finding the most appropriate canditate for the treatment of Niemann

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Recent Posts

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  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng
  • New book on beta-cyclodextrin and its derivatives

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Top Posts

  • Innovative Titanium Coatings for Enhanced Dental Implants
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers
  • New cyclodextrin with orphan drug designation: SBECD
  • Cyclodextrin dimers to treat atherosclerotic plaques by targeting various forms of cholesterol
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Old but Gold (literally)!
  • Lanosterol eye drops for cataract treatment
  • Selecting a non-interacting buffer for α-cyclodextrin containing solutions
  • International Summer School on Cyclodextrins

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