Mirror-Image β-l-Cyclodextrin as a Chiral Pseudophase in Capillary Electrophoresis.
In this study, the chiral separation of 38 analytes was investigated with capillary electrophoresis and the enantiomeric selectivity was compared
Tag: enantioseparation
Biosignature Detection from Amino Acid Enantiomers with Portable Gas Chromatography Systems for Spaceflight Missions
This paper presents developments in chiral stationary phase coatings for microelectromechanical system gas chromatography (MEMS GC). Three commercial columns coated
Mirror-Image Cyclodextrins
Natural cyclodextrins (CDs) have waited for about 130 years until they could see their mirror image when looking into the
Differentiating enantiomers by mass spectrometry? (Yes)
Chemists just reported that it is possible to use mass spectrometry — a technique commonly used to identify molecules by
Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode
Due to the different pharmacokinetic and pharmacodynamic effect of enantiomers, to develop novel enantioselective methods are crucial. The gold standard
Enhanced Chiral Recognition Abilities of Cyclodextrin Covalent Organic Frameworks via Chiral/Achiral Functional Modification
β-Cyclodextrin covalent organic frameworks (β-CD COFs) show great potential in enantioseparation due to their uniformly distributed chiral recognition sites and
The role of deep eutectic solvents in chiral capillary electrokinetic chromatography: a comparative study based on α-cyclodextrin chiral selector
Deep eutectic solvents (DESs) are emerging as potential candidates as additives/modifiers in chiral electrokinetic chromatography (EKC). However, the true role
CDs as Dominant Chiral Selective Agents in the Capillary Separation Techniques
This review paper shows the dominant role of the cyclodextrins in the chiral separations using capillary columns (GC, SFC, CE).
Single Isomer N-Heterocyclic Cyclodextrin Derivatives as Chiral Selectors in Capillary Electrophoresis
In order to better understand the chiral recognition mechanisms of positively charged cyclodextrin (CD) derivatives, the synthesis, the pKa determination by 1H
Review on cyclodextrin-based functional systems for biomedical applications
In this review Xu et al. (2021) highlight the characteristics and advantages of CDs as a starting point to design