Multifunctional Molecular Hybrids Photoreleasing Nitric Oxide: Advantages, Pitfalls, and Opportunities
The multifaceted role nitric oxide (NO) plays in human physiology and pathophysiology has opened new scenarios in biomedicine by exploiting
Tag: NO release
Pulmonary Vasodilating Effects of a New Drug Formulation Containing a NO Donor Metabolite (SIN-1A) stabilized by CD
Sin1A is an unstable NO releasing metabolite of Molsidomine. Molsidomine is a prodrug that undergoes first-pass metabolism in the liver,
Nitric Oxide-Releasing Topological Supramolecular Nanocarriers with sliding CD units against MRSA
Polymeric systems that provide cationic charges or biocide-release therapeutics are used to treat the bacteria-infected wound. However, most antibacterial polymers
Inclusion Complexation of S-Nitrosoglutathione for Sustained NO Release and Reduced Device Infection
S-nitrosoglutathione (GSNO) is a non-toxic nitric oxide (NO)-donating compound that occurs naturally in the human body. The use of GSNO
Beta-Cyclodextrin/L-Arginine/Au Nanomotors for Atherosclerosis
Most of the current non-pharmacological treatment strategies for atherosclerosis (AS) suffer from poor penetration into the plaque and only aim
Visible Light-Activatable Cyclodextrin-Conjugates for the Efficient Delivery of Nitric Oxide with Fluorescent Reporter and their Inclusion Complexes with Betaxolol
Novel multifunctional drug delivery systems were developed by the Sortino’s group [1]. βCD-NBFNO1 and βCD-NBFNO2, covalently integrating an N-nitroso amino-nitro-benzofurazan
Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1)
Introduction: Antimicrobial resistance is one of the major scourges for healthcare worldwide, therefore novel investigational approaches are needed to potentiate and
NO-delivering fluorescent beta-cyclodextrin polymer
A novel water-soluble β-cyclodextrin branched polymer covalently integrating a fluorescein moiety and a nitric oxide (NO) photodonor within its macromolecular
Cyclodextrin News Year in Review 2018
The CDNews blog was created in July and after a short period of trial it started in September. During this
NO-releasing cyclodextrins
Nitric oxide (NO) is a signaling molecule produced by almost all types of organisms ranging from bacteria to plants and