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Tag: autophagy

March 12, 2022 Drug delivery

Cancer-Related Intracellular Signalling Pathways Activated by Doxorubicin/Cyclodextrin-Graphene-Based Nanomaterials

In the last decade, nanotechnological progress has generated new opportunities to improve the safety and efficacy of conventional anticancer therapies.

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February 23, 2022 CD as API / Pharma applications

HPBCD for Treatment of Parkinson Disease

The recent work of Jarazo et al. demonstrates that HP-β-CD ameliorates the dopaminergic neuronal loss phenotype, confirming the therapeutic potential

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November 23, 2021 CD as API / Pharma applications

Folate-appended CDs in cancer therapy

The team of Motoyama in Kumamoto has recently published new results on folate-appended CDs in leukemia and ovarian cancer (1,2).

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November 22, 2021 Uncategorized

Use of cyclodextrins in diseases and disorders involving phospholipid dysregulation

A patent application by Knut M. Wittkowski (ASDERA LLC, US) entitled “Use of cyclodextrins in diseases and disorders involving phospholipid

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October 21, 2021 CD as API / Pharma applications

Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment

OrganoTherapeutics in collaboration with University of Luxemburg has published interestingin vitro and in vivo results on the effects of HPBCD

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February 4, 2021 CD as API / Drug delivery / Events

Press Release – Development of Autophagy Inducing Cyclodextrin Derivatives for Aging-associated Diseases

CycloLab Cyclodextrin R&D Ltd. proudly announces winning of a national grant about the development of cyclodextrin-dervatives for autophagy-associated neurodegenerative diseases.

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October 5, 2020 CD as API / Pharma applications

An antibody–supermolecule conjugate for cancer chemotherapy

In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to

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September 21, 2020 CD as API / Pharma applications

Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets.

The plasma membrane microdomain lipid rafts have been found by researchers to be involved in the replication cycle of numerous

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July 7, 2020 CD as API / Pharma applications

Cyclodextrin to prevent abdominal aortic aneurysm

The scientists at University of Michigan Medical Center, Ann Arbor, MI published on a new  application of hydroxypropyl beta-cyclodextrin (HPβCD)

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February 6, 2020 CD as API / Pharma applications

Antiviral effect of C-reactive polymer and methyl beta-cyclodextrin via blocking autophagy through interactions with cell membrane cholesterol

Spanish researchers recently published on the mechanisms involved in antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring

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Recent Posts

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  • Oligomer Sensor Nanoarchitectonics for “Turn-On” Fluorescence Detection of Cholesterol at the Nanomolar Level
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Top Posts

  • Recent important review articles from Thorsteinn Loftsson's group about ophthalmic drug delivery
  • V International Summer School on Cyclodextrins
  • Alpha-CD powder and tablets in Japan
  • CIDALTEX® ANTIVIRAL MASKS DURING THE COVID-19 PANDEMIC
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Matthieu SOLLOGOUB at ICS 20
  • GRAS status of CD derivatives
  • Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
  • Application of cyclodextrin containing sliding-ring polymers in oil-well cement
  • Egg-Free Bakery - Recommendation from Wacker

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