A “Ship-in-a-Bottle” strategy to enhance solubility and bioavailability
Metal-organic frameworks (MOFs) consisting of γ-cyclodextrin and potassium were used to incorporate folic acid clusters. The molar ratio of folic
Category: Pharma applications
Cyclodextrins: Properties and Industrial Applications
A book published by Wiley in 2017 is one of the comprehensive reviews collecting the up-to-date knowledge on cyclodextrins. It
Effect of cosolvent on the complexation of caffeic acid
Caffeic acid is a phenolic compound found in several plants and fruits including coffee beans. It has high nutraceutical value
Opinion leaders of CD society getting together in Budapest
In the recent two weeks, Cyclolab had the pleasure to welcome two prominent pioneers of cyclodextrin research, Prof. Loftsson from
Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery
In the laboratory of C. M. O’Driscoll (University College Cork), an antibody targeted cyclodextrin-based siRNA delivery vector (CD.DSPE-PEGFab) was developed
NO-releasing cyclodextrins
Nitric oxide (NO) is a signaling molecule produced by almost all types of organisms ranging from bacteria to plants and
Mannose with anti-cancer effect
In a recently published Nature report it was investigated how tumor cells respond to different forms of sugar [1]. It
Cyclodextrins involved in clinical trials to start
According to clinicaltrials.gov, currently, there are 14 cyclodextrin-related clinical trials that in the status of i) Not yet recruiting, ii)
Sage Therapeutics Announces FDA Advisory Committee Votes 17-1 in Support of Benefit-Risk Profile of ZULRESSO™ (brexanolone) Injection for Treatment of Postpartum Depression
If approved, ZULRESSO would be the first medicine specifically indicated for the treatment of postpartum depression (PPD) Sage Therapeutics (NASDAQ:
Melinta Therapeutics Announces Positive Top-Line Results in Phase III Trial of Baxdela® (delafloxacin) for Treatment of CABP
Melinta Therapeutics, Inc. (NASDAQ: MLNT), a commercial-stage company discovering, developing and commercializing novel antibiotics to treat serious bacterial infections, announced positive