Selecting a non-interacting buffer for α-cyclodextrin containing solutions
The article examines the effects of twelve pharmaceutically relevant buffers on the inclusion complex between α-cyclodextrin (α-CD) and 1,9-nonanediol using
Category: Drug delivery
Repurposing neurological drugs for brain cancer therapeutics
Treatment of glioblastoma (GBM) presents significant challenges due to its high degree of heterogeneity and poor prognosis. Recurrence of the
Cyclodextrin-Based Nanotransporters as a Versatile Tool to Manage Oxidative Stress-Induced Lung Diseases
Oxidative stress is one of the key elements in lung-related complications such as cystic fibrosis, acute lung injury, pulmonary hypertension,
A Critical Evaluation of Genuine Cyclodextrin- containing Products in the Post-soviet Market
This study examines suboptimal formulation practices involving cyclodextrins (CDs) in medicinal products across the post-Soviet region, with a focus on
Novel plug-in capsule device for pulsatile release from meloxicam-β-cyclodextrin-pectin ternary complex
Chronomodulated diseases demonstrate circadian fluctuations. Conventional dosage forms are inadequate for mitigating these ailments; instead, time-scheduled drug release is necessary
Cyclodextrins as Multifunctional Platforms in Drug Delivery and Beyond: Structural Features, Functional Applications, and Future Trends
This review outlines the structural features of native CDs and their chemically modified derivatives, emphasizing the influence of functionalization on
Allopregnalonone/SBECD Complex in Clinical Trial for Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in Post Traumatic Stress Disorder
Clinical trial NCT07079761 may help us understand treatable factors that increase risk for chronic or treatment-resistant Post Traumatic Stress Disorder
Development of a nasal spray based on cyclodextrin/hydrophobically-modified hydroxypropyl-methyl cellulose for the prevention of viral respiratory infections
The work aims to develop mucoadhesive and thermo-responsive in situ gelling systems, using hydrophobically-modified hydroxypropyl-methyl cellulose (Sangelose, SG) and beta-cyclodextrin
Harnessing Organoid Platforms for Nanoparticle Drug Development
Cancer nanomedicine holds transformative potential, but its clinical translation remains hindered by the lack of preclinical models that accurately mimic
Low levels of γ-CD (β-CD:γ-CD = 1:0.1) to effectively stabilize amorphous Flurbiprofen formulations
This study aimed to develop stable amorphous inclusion complexes of flurbiprofen (FP, used as a model drug) with two different