Patent applications related to synthesis of heptakis(2,6-di-O-alkyl)-beta-cyclodextrin by CycloLab
45 years ago, Szejtli et al. reported on the synthesis of heptakis(2,6-di-O-methyl)-beta-cyclodextrin using dimethyl sulfate as alkylating agent in a
Category: Drug delivery
A new chemo immunotherapy combination based on CD nanosponges against pancreatic cancer
Pancreatic cancer is resistant not only to chemotherapy but also to immunotherapy; therefore, identifying strategic alternatives is still necessary. Recently,
Mucoadhesive hydrogel film based on cyclodextrin cross-linked with thiolated hydroxyethyl cellulose for mucosal delivery of cisplatin
The efficacy of cisplatin (CTN) is limited due to its short half-life and toxic side effects. This study aimed to
One step back: what we learned from the thiolation of cyclodextrins and how we can apply that to starch
Thiolated oligomers and polymers, also known as thiomers, are valuable tools for non-parenteral drug delivery.1-3 Due to the cysteine-rich segments
Hydrogel containing oxidized beta-cyclodextrin for in-vivo release of a medication: a sheep model
Cyclodextrins are seldom used in sustained-release formulations, as they are more commonly associated with rapid drug delivery. However, cyclodextrin complexes
Special issue: Recent Trends in Carbohydrate-Based Therapeutics
Carbohydrates are encountered in many applications across diverse fields, including glycobiology, pharmaceuticals, genetics, material chemistry, polymer chemistry, and the food
Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins
Fenofibric acid (FFA) exhibits notable anti-inflammatory potential. This research assesses the anti-inflammatory effects of FFA, both in its standalone form
Call for Book Chapters – Cyclodextrin-Based Books (Wiley & Springer)
📘 Cyclodextrins in Cancer Therapy (Published by Wiley)📗 Cyclodextrins in Environmental Remediation (Published by Springer Nature) These volumes aim to
Magnetic Carboxymethyl-β-Cyclodextrin nanocarrier for targeted sitagliptin delivery
This study aimed to magnetize β-cyclodextrin (β-CD) to serve as a nanocarrier for sitagliptin (Sita) in targeted drug delivery applications.
Multifunctional Fluorescent β-cyclodextrin Hydrogel for pH-controlled Drug Release and Environmental Sensing
Smart biobased hydrogels have become increasingly significant in controlled drug delivery due to their ability to improve bioavailability and minimize