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Tag: Synthesis

May 31, 2022 Analysis / CD derivatives / Non-pharma applications

Enhanced Chiral Recognition Abilities of Cyclodextrin Covalent Organic Frameworks via Chiral/Achiral Functional Modification

β-Cyclodextrin covalent organic frameworks (β-CD COFs) show great potential in enantioseparation due to their uniformly distributed chiral recognition sites and

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April 21, 2022 CD derivatives

Superdimer guanidino-γ-cyclodextrin

Octakis-6-guadinidino-γ-cyclodextrin (gguan) hydrochloride in the presence of phosphates crystallises from aqueous solution in the unprecedented form of a superdimer (dimer-within-a-dimer).

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April 6, 2022 CD derivatives

Cyclodextrin-Oligocaprolactone Derivatives-Synthesis and Advanced Structural Characterization by MALDI Mass Spectrometry

The β-cyclodextrin derivatization with short oligoester chains, through convenient synthesis methods, leads to highly water-soluble and biodegradable compounds. Cyclodextrins have

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February 24, 2022 CD derivatives

Magic cyclodextrins turn blue on rubbing: mechanochromism

Prof. Aoki wrote this short summary for our blog on their unique achievement: In this study, we have used cyclodextrins

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February 14, 2022 CD derivatives / Drug delivery / Pharma applications

D-maltose clicked to β-cyclodextrin: preparation and its application as a biocompatible drug delivery nanovehicle

D-maltose-clicked derivative of β-cyclodextrin (β-CD-M) was synthesized to compare and investigate its capability as an anticancer drug nanocarrier [1]. The

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December 16, 2021 CD derivatives

Ronald C.D. Breslow (1931–2017)

Reviewed herein are key research accomplishments of Professor Ronald Charles D. Breslow (1931–2017) throughout his more than 60 year research career.

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November 29, 2021 CD derivatives / Drug delivery / Pharma applications

Synthesis and biological evaluation of novel β-cyclodextrin-fluvastatin conjugates

Drugs that may regulate lipid metabolism and lower cholesterol, such as statins (drugs that reduce de novo cholesterol synthesis) or

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September 24, 2021 CD as API / CD derivatives / Events / Pharma applications

Meet the Experts: Cyclodextrins as active ingredients in the 21st century – Webinar of CycloLab

After the great success of the webinar held in May, 2021 a next webinar organized by CycloLab will be held

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September 14, 2021 Analysis / CD derivatives

Single Isomer N-Heterocyclic Cyclodextrin Derivatives as Chiral Selectors in Capillary Electrophoresis

In order to better understand the chiral recognition mechanisms of positively charged cyclodextrin (CD) derivatives, the synthesis, the pKa determination by 1H

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September 1, 2021 CD derivatives

A review on mono-6 substituted cyclodextrins

The huge literature on synthesis and applications of mono-6-substituted CDs has been reviewed by Kasal and Jindrich selecting the most

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  • Virus-Mediated Self-Assembly of Functional Cyclodextrins for Antiviral Inhibition

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Top Posts

  • Phosphorylated Beta-cyclodextrin as a New Bone-Targeting Drug Delivery System Could Change the Treatment of Osteoporosis and Other Bone Diseases
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  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • Potential Glioblastoma Therapy with Cationic Cyclodextrin Polymers as Drug Delivery Excipients
  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • Wasabi's bioactive component 6-MSITC formulated with alfa-cyclodextrin improved memory proven in clinical trial.
  • HPaCD against Alzheimer Disease
  • HPBCD was tested as a possible therapeutic agent in Amyotrophic Lateral Sclerosis (ALS) model
  • Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress

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