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Tag: solubility

January 5, 2023 Drug delivery / Pharma applications

Inclusion complexes of the steroid hormones 17β-estradiol and progesterone with β- and γ-cyclodextrin hosts

This study addresses the poor solubility of two potent steroid hormones, 17β-estradiol (BES) and progesterone (PRO), via their complexation with

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July 20, 2022 Drug delivery / Pharma applications

Melatonin/Cyclodextrin Inclusion Complexes: A Review

Melatonin (MLT) is involved in many functions of the human body, mainly in sleeping-related disorders. It also has anti-oxidant potential

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April 27, 2022 Analysis

Cyclodextrins interfere in the ORAC method to measure antioxidant activity

                Oxygen Radical Absorbance Capacity (ORAC) is a water-based method commonly used to determine the antioxidant capacity of bioactive compounds

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December 20, 2021 Drug delivery / Pharma applications

Pilocarpine eye drops (Vuity)

VUITY™ may help elderly people to read without their reading glasses [1] Elderly people can soon read without the help

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March 3, 2021 Drug delivery / Pharma applications

Improving Bioavailability & Solubility

Drug Development & delivery published on the virtual 2020 Global Drug Bioavailability Enhancement Summit, which this past December showcased novel

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October 30, 2020 Pharma applications

Technological evolution of cyclodextrins in the pharmaceutical field

Tthe evolution of CD-based pharmaceutical technologies was analyzed, using patent data as the technical source, through a text-mining approach based

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October 7, 2020 Drug delivery / Pharma applications

Inclusion complex of chrysin with sulfobutyl ether-β-cyclodextrin

The work of Kulkarni and Belgamvar [1] demonstrates the impact of sulfobutyl ether-β-cyclodextrin (SBE-β-CD) complexation on the solubility, dissolution and

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November 27, 2019 CD derivatives

Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies

The so-called “intrinsic” solubility of cyclodextrins (CDs) and their derivatives is always one of the first and important questions from

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January 28, 2019 Drug delivery / Pharma applications

Cyclodextrins in veterinary medicine (Part 1)

It is well known, that cyclodextrins have many different applications. Can they be used in veterinary medicine? Well, yes and

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December 13, 2018 Drug delivery / Food / Non-pharma applications

Effect of cosolvent on the complexation of caffeic acid

Caffeic acid is a phenolic compound found in several plants and fruits including coffee beans. It has high nutraceutical value

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  • Bacteroides uniformis and its preferred substrate, α-cyclodextrin, enhance endurance exercise performance in mice and human males
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  • Waterproof and durable luminescent textiles with HPBCD for marine rescue
  • New book: Cyclodextrins - new Perspectives
  • Small anticancer drug release by light
  • γ-Cyclodextrin/Epigallocatechin-3-gallate Inclusion Complexes as Efficient Antioxidants for Preservation of Shrimp Surimi Products
  • Cyclodextrin Metal-Organic Framework as a Broad-Spectrum Potential Delivery Vehicle for the Gasotransmitters
  • MIT scientists filed patent for HPBCD treatment in Alzheimer's disease
  • Pilocarpine eye drops (Vuity)
  • Published compilation of the list of approved cyclodextrin-containing drug products

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