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Tag: protein

December 22, 2025 Drug delivery / Pharma applications

HPBCD and polysorbate containing formulation to eliminate aggregation of a potent osteogenic protein, recombinant human NELL-1

This study utilized a four-stage rational formulation development approach to mitigate aggregation and stabilize a high molecular weight protein, rhNELL-1.

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November 16, 2023 Drug delivery / Pharma applications

Unraveling the interaction of drug (Diflunisal) with cyclodextrin and protein (Lysozyme) by fluorescence spectroscopy

Understanding the interaction between the drug:carrier complex and protein is essential for the development of a new drug-delivery system. However,

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October 20, 2023 Events

European Symposium on Controlled Drug Delivery

The 17th edition of the European Symposium on Controlled Drug Delivery will be held on April 10 – 12, 2024

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August 9, 2023 Pharma applications

Design of a Cyclodextrin Bioproduction Process Using Bacillus pseudofirmus and Paenibacillus macerans

Cyclodextrin-glucosyl-transferase (CGTase) is amongst the most important enzymes used in CD biosynthesis. However, the bioproduction of CDs still faces challenges

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November 30, 2021 CD derivatives / Life sciences

Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the KV1.3 Ion Channel Independent of Membrane Cholesterol Extraction

Effects of CDs exerted on cellular functions are generally thought to originate from reductions in cholesterol levels. Potential direct, ligand-like

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January 13, 2020 Drug delivery / Gene delivery

Casting Light on Intracellular Tracking of a New Functional Graphene-Based MicroRNA Delivery System by FLIM and Raman Imaging

The theranostic ability of a new fluorescently labeled cationic cyclodextrin−graphene nanoplatform (GCD@Ada-Rhod) was investigated by studying its intracellular trafficking and

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September 10, 2018 Drug delivery / Pharma applications

Cyclodextrin to formulate proteins – dream or reality

Several cyclodextrins have been claimed by dozens of papers including huge works of Serno [1] and Hartl [2] to be

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Top Posts

  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Events of American Cyclodextrin Consortium
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • Using cyclodextrin is not rocket science...except for NASA researchers.
  • HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • Lanosterol eye drops for cataract treatment
  • Bridion® injection now approved for patients of all ages
  • Febreeze with double HPBCD concentration for kitchen smell
  • CD-enabled active food packaging in the recent literature

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