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Tag: polyrotaxanes

March 10, 2026 CD as API / CD derivatives / Pharma applications

Toxic effects and cellular uptake of functional polyrotaxanes. The little we have learned and the many unknowns still waiting to be discovered.

Cyclodextrins are commonly used as excipients in modern drug delivery, but they also have a less common role as active

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November 12, 2025 CD as API / CD derivatives / Pharma applications

Methyl BCD-based supramolecular polyrotaxane as theranostic in anticancer immunotherapy

Despite the tremendous therapeutic promise of activating stimulators of interferon genes (STING) enable to prime robust de novo T-cell responses,

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April 29, 2024 CD derivatives / Drug delivery / Pharma applications

Synthesis of cyclodextrin-based polyrotaxanes and polycatenanes for supramolecular pharmaceutical sciences

This nicely illustrated review article summarizes the syntheses and structural analyses of CD polyrotaxanes and polycatenanes to facilitate their applications

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June 24, 2022 Events / Non-pharma applications / Other industrial use

Prof. Kohzo Ito at ICS 20

Kohzo Ito, professor at Tokyo University and director of Advanced Softmaterials Inc. gave a plenary lecture on the 20th International

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July 20, 2021 Drug delivery / Pharma applications

Age-related ocular conditions: Current treatments and role of cyclodextrin-based nanotherapies

Age-related eye disorders are chronic diseases that affect millions of people worldwide. They cause visual impairment and, in some cases,

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December 6, 2019 Drug delivery / Pharma applications

Bio-soft cyclodextrin materials

A recent review of prof. Mazzaglia’s group gives an overview on CD-based nanomaterials of biological relevance focusing on CD self-assembly

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Recent Posts

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  • Handbook of Cyclodextrin-Based Enabling Technologies for Overcoming the Solubility and Bioavailability Limitations of Class II, III and IV Drugs
  • Call for Chapters: Cyclodextrins for Next-Generation Electronics and Energy Storage
  • Call for Chapters: Cyclodextrins in Nutraceuticals 

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Top Posts

  • Enhancing Emulsifying Properties of HPBCD with octenyl succinic anhydride
  • 19th International Symposium on Macrocyclic and Supramolecular Chemistry 2025
  • Comparison of the siRNA and mRNA Carrying Capacity of Quaternary Ammonium β-Cyclodextrin Polymer and Polyethylenimine
  • Trans sodium crocetinate/cyclodextrin to increase diffusion of oxygen
  • Cyclodextrins Across the Eye-Care Spectrum
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Solventless Crosslinking of Chitosan, Xanthan, and Locust Bean Gum Networks Functionalized with β-Cyclodextrin
  • PEG-β-Cyclodextrin polymer-based formulation to increase the antiangiogenic activity of rutin in vivo
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Characterization of the substitution pattern of 2-hydroxypropyl-β-cyclodextrin using NMR spectroscopy

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