Disruption of Lipid Sorting and Endosomal Transport in Cyclodextrin-mediated Cytotoxicity
The effects of native and modified CDs in human renal proximal tubule cells was studied using complementary imaging, flow cytometry,
Tag: phospholipid
Dimethyl-α-cyclodextrin induces capacitation by removing phospholipids from the plasma membrane of mouse sperm
Dimethyl-alpha-CD (DMACD) was found to enhance sperm fertilization ability by removing phospholipids. It was concluded that in addition to the
HPaCD against Alzheimer Disease
HP-beta-cyclodextrin (HPbCD) is currently in clinical trials against Niemann-Pick Disease Type C (NPC) and Alzheimer’s Disease (AD) and these trials
Alpha-cyclodextrin and Hydroxytyrosol against SARS-CoV-2 infection
In the last year, the Cyclodextrin News reported on an oral spray containing alpha-cyclodextrin and hydroxytyrosol developed by Italian researchers
Antibody-Targeted Cyclodextrin-Based Nanoparticles for siRNA Delivery
In the laboratory of C. M. O’Driscoll (University College Cork), an antibody targeted cyclodextrin-based siRNA delivery vector (CD.DSPE-PEGFab) was developed
HPαCD More Effective than HPβCD Against Breast Cancer
Wittkowski et al. recently published their results on re-evaluation of three genome-wide association studies using computational biostatistics approach. The genetic