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Tag: NMR

April 24, 2024 CD as API / Drug delivery / Pharma applications

Characterization of the substitution pattern of 2-hydroxypropyl-β-cyclodextrin using NMR spectroscopy

2-Hydroxypropyl-β-cyclodextrin (HPBCD) is one of the most important cyclodextrin derivatives, finding extensive applications in the pharmaceutical sector. Beyond its role

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April 20, 2022 CD derivatives / Drug delivery / Pharma applications

Dramatically Increased Binding Constant of Water-Soluble Cyclodextrin Hyperbranched Polymers

The polymerization of cyclodextrin (CD) with epichlorohydrin (ECH) dramatically increases the binding constant of CD to vanillin, from 55 to

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April 12, 2022 Drug delivery / Pharma applications

Sulfobutylation of Beta-Cyclodextrin Enhances the Complex Formation with Mitragynine: An NMR and Chiroptical Study

Mitragynine (MTR), the main indole alkaloid of the well-known plant kratom (Mitragyna speciosa) is a partial agonist on the opioid

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April 6, 2022 CD derivatives

Cyclodextrin-Oligocaprolactone Derivatives-Synthesis and Advanced Structural Characterization by MALDI Mass Spectrometry

The β-cyclodextrin derivatization with short oligoester chains, through convenient synthesis methods, leads to highly water-soluble and biodegradable compounds. Cyclodextrins have

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December 2, 2021 Uncategorized

Molecular interactions in remdesivir-cyclodextrin systems

In a recently published study intermolecular interactions of remdesivir and various cyclodextrin derivatives were characterized by extensive NMR spectroscopy. The

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August 30, 2021 Drug delivery / Pharma applications

Doxorubicin-Loaded Metal-Organic Frameworks Nanoparticles with Engineered Cyclodextrin Coatings

Recently developed, nanoscale metal-organic frameworks (nanoMOFs) functionalized with versatile coatings are drawing special attention in the nanomedicine field. Core–shell MIL-100(Al)

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November 3, 2020 E-ducation

Chapter 3: Professor Casu and Cyclodextrins

Chapter 3 in the recently published book on the history of cyclodextrin is on Professor Benito Casu (1927-2016), who was

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May 8, 2020 CD derivatives / Drug delivery / Pharma applications

Chlorpromazine complexation with Sugammadex – an extremely high complexation constant

An in press paper on detailed ITC and NMR study of chlorpromazin complexation with various cyclodextrins reports on an unexpected

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December 11, 2018 E-ducation

Symmetrical conformers of naturally occurring cyclodextrins

Due to the high flexibility of the glucose units CDs can be described by many conformers. Recent advances in high-performance

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Recent Posts

  • Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress
  • CDs as Modulators of Regulated Cell Death: Implications for Immunometabolism and Therapeutic Innovation
  • Nanotechnology World Conference 2026
  • Hybrid Cyclodextrin Nanosponges Meet Nanoporous Gold: A Step Forward in Sensing Platforms
  • Innovative Cyclodextrin Composition for Canine Odour Neutralization

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Top Posts

  • Methyl salicylate/methyl-β-cyclodextrin inclusion complex modulates plant defense against cold and heat stress
  • CDs as Modulators of Regulated Cell Death: Implications for Immunometabolism and Therapeutic Innovation
  • The story of cyclodextrin metal–organic frameworks and their applications from Nobel-prize laureate, F. Stoddart
  • Improving Drug Bioavailability with Cyclodextrin Complexes: An integrative meta-modeling approach
  • Innovative Cyclodextrin Composition for Canine Odour Neutralization
  • Lanosterol eye drops for cataract treatment
  • One-pot synthesis of γ-cyclodextrin of high purity from non-food cellulose without the use of complexing agents
  • Hybrid Cyclodextrin Nanosponges Meet Nanoporous Gold: A Step Forward in Sensing Platforms
  • Recent Advances in Intranasal Administration for Brain-Targeting Delivery
  • Three Birds, One Excipient: Development of an Improved pH, Isotonic, and Buffered Ketamine Formulation for Subcutaneous Injection

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