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Tag: Niemann-Pick disease type C

March 2, 2026 CD as API / Pharma applications

Beren Therapeutics’Adrabetadex Received FDA Acceptance for infantile-onset Niemann Pick Disease

Beren Therapeutics Announced FDA Acceptance of its New Drug Application for Adrabetadex in Infantile-Onset Niemann-Pick Disease Type C. Beren Therapeutics

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October 13, 2025 CD as API / Pharma applications

JIC Venture Growth Investments Invests in Beren Therapeutics P.B.C. to Advance Innovative, Cyclodextrin-based Therapeutics

JIC Venture Growth Investments (VGI) announced that it has invested in Beren Therapeutics P.B.C. (“Beren Therapeutics”). Beren Therapeutics is developing

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September 22, 2025 CD as API / Pharma applications

7 of 9 patients showed stabilization or improvement: preliminary data from ongoing Phase 3 TransportNPC™ clinical trial

Rafael Holdings, Inc. announced that data from Cyclo Therapeutics’ Phase 3 TransportNPC™ open-label, single-arm sub-study evaluating Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) for Niemann-Pick

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August 27, 2024 CD as API / Pharma applications

Rafael Holdings and Cyclo Therapeutics merge to advance Niemann-Pick drug as FDA rival decision nears

Rafael Holdings and Cyclo Therapeutics on Thursday announced a merger agreement as they look to spur development of their Niemann-Pick

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August 8, 2024 CD as API / Pharma applications

Cyclodextrins as therapeutic drugs for treating lipid metabolism disorders

This study sought to systematically compare the efficacy and mechanism of cyclodextrins as drug interventions in lipid metabolism diseases, potentially

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April 8, 2024 CD as API / Pharma applications

Alterations in Proteostasis Mechanisms in Niemann–Pick Type C Disease

Niemann–Pick Type C (NPC) represents an autosomal recessive disorder with an incidence rate of 1 in 150,000 live births, classified

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January 9, 2024 CD as API / Pharma applications

Merger of Cyclo Therapeutics and Applied Molecular Transport

Cyclo Therapeutics, (Cyclo) a clinical stage company focused on developing therapies for rare and neurological diseases with limited treatment options,

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December 5, 2023 CD as API / Pharma applications

Molecular Mind Games: The Medicinal Action of Cyclodextrins in Neurodegenerative Diseases

This work presents the most recent advances in the research and clinical use of HPβCD against Niemann–Pick disease, a congenital

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October 4, 2023 CD as API / Pharma applications

The background story on how the HPBCD became and orphan drug (Hommage’ a Families, Parents)

The Pulitzer Prize-winning Wall Street Journal science- and health writer, Amy Dockser Marcus, in her new book „We the Scientists”

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March 16, 2023 CD as API / CD derivatives / Life sciences / Pharma applications

Patent application: gamma-cyclodextrin-based polymer for prevention or treatment of cholesterol metabolism-related diseases

RENATUS, a South Korea-based pharma company pioneering next generation cyclodextrin-based therapies for the safe treatment of cholesterol-associated diseases recently filed

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  • Special issue: “Synthesis, Analysis and Applications of Cyclodextrins and Their Derivatives”
  • Multiscale mechanistic analysis of reversible cross-linking polymers based on host–guest interactions
  • Redox responsive cyclodextrin-based drug delivery systems: a special insight to glutathione responsive CD-nanosponges

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Top Posts

  • Cationic Cyclodextrin-Based Carriers for Drug and Nucleic Acid Delivery
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  • Special issue: “Synthesis, Analysis and Applications of Cyclodextrins and Their Derivatives”
  • Lanosterol eye drops for cataract treatment
  • Methyl alpha-CD for lipid exchange in cell membrane
  • Chemical modification of β-cyclodextrin towards hydrogel formation
  • Oculis: eye drops with Dexamethasone/gamma-CD complex Phase 3 study concluded soon
  • Cyclodextrins to preserve and analyze whisky flavor
  • 45 years of paracetamol (acetaminophen)–beta-cyclodextrin complex history - now used in versatile pharmaceuticals
  • MIT scientists filed patent for HPBCD treatment in Alzheimer's disease

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