CD in prevention of dengue-induced lethality
Annexin A1 (AnxA1) was identified as an endogenous regulator of inflammation in dengue. Treatment with the AnxA1 peptidomimetic, Ac2-26, improved
Tag: antiinflammatory effect
Cyclodextrin-based materials for pulmonary delivery: Insights and challenges
The literature provides a large range of information on the manufacturing of CD-based materials for pulmonary delivery, the characterization of
Clinical Effectiveness, Safety, and Compliance of Two Compounded Formulations of Tacrolimus Eye Drops: An Open-Label, Sequential Prospective Study
Ophthalmic tacrolimus compounded formulations are usually made from the commercial intravenous presentation, which contains ethanol as a solubilizer due to
Impacts of the Methylated Cyclodextrin KLEPTOSE® CRYSMEB on Inflammatory Responses in Human InVitro Models
KLEPTOSE® CRYSMEB is a methylated cyclodextrin derivative displaying less methylated group substitution than randomly methylated cyclodextrin. It has demonstrated an
Antinociceptive Effect of a p-Cymene/β-Cyclodextrin Inclusion Complex in a Murine Cancer Pain Model
Pain is one of the most prevalent and difficult to manage symptoms in cancer patients, and conventional drugs present a
Glutathione-depleted cyclodextrin pseudo-polyrotaxane nanoparticles for anti-inflammatory oxaliplatin (IV) prodrug delivery and enhanced colorectal cancer therapy
Oxaliplatin (Oxa) is the first-line chemotherapeutic drug for the treatment of colorectal cancer (CRC). However, long-term Oxa chemotherapy can induce
Low doses of the typically toxic gas carbon monoxide as a new treatment for diabetic vision loss
Carbon monoxide is typically dangerous because it binds to the hemoglobin in red blood cells with a much higher affinity
Hot-melt extrusion for cyclodextrin inclusion complex of a multicomponent natural product
This study aimed to investigate whether hot-melt extrusion (HME) processing can promote molecular encapsulation of a multi-component natural product composed
Antidepressant/BCD complexes
The paper Aree [1] starts with an interesting statistics on depression (for the references see the original paper): Depression is
The different possibilities of cyclodextrins to manage inflammation
Inflammation is one of the usual biological responses to different pathologies or stimuli. As the incidence of inflammation related diseases