Self-assembly of Cationic Permethylated Cyclodextrins
A highly diastereoselective synthesis of cationic permethylated α- and β-cyclodextrins (α-CDs and β-CDs), incorporating a quaternary ammonium unit bridging two
Tag: Aggregation
Cyclodextrin-Driven Drug Deaggregation
The poor aqueous solubility of niclosamide (Nic), a drug with broad therapeutic potential beyond its original antiparasitic use, presents a
Hydroxypropyl β Cyclodextrins Effects on Self-Assembly of Cyclic Peptide, Lanreotide Acetate, in Water and Subsequent Release rate from an in vitro Emulator of Subcutaneous Delivery
Most of peptide drugs are often delivered subcutaneously. The significant barrier in this type of peptide administration is the high
CD-based diagnostic tool for atherosclerotic plaque
Atherosclerosis (AS), a pathological cause of cardiovascular disease, results from endothelial injury, local progressive inflammation, and excessive lipid accumulation. AS
The Single Toxin Origin of Alzheimer’s Disease and Other Neurodegenerative Disorders Enables Targeted Approach to Treatment and Prevention
New data suggest that the aggregation of misfolded native proteins initiates and drives the pathogenic cascade that leads to Alzheimer’s
A review on sodium sulfobutylether-β-cyclodextrin (SBECD)
This review on SBECD and its complexes summarizes the properties and applications with special emphasis on the effect of degree
Anomalous Properties of Cyclodextrins and Their Complexes in Aqueous Solutions
Since their discovery, CDs have been the subject of close to 100,000 publications, including about 61,000 peer-reviewed scientific articles and
Two birds, one stone: host-guest complex of indocyanine green–β-cyclodextrin for fundus angiography
Indocyanine green (ICG) angiography is of great importance for ophthalmic diagnostic applications and is mainly used to check for choroidal
Recent important review articles from Thorsteinn Loftsson’s group about ophthalmic drug delivery
Thorsteinn Loftsson recently published a series of review articles which sums up his advances in ophthalmic drug delivery. This blog
Electrospun Nanofibers for Drug Delivery Application
A recently published book titled “Applications of Polymer Nanofibers” (Wiley, 2022) contains a chapter on “Electrospun Nanofibers for Drug Delivery