Supramolecular Diagnostic Tool: A Freshly Approved HPBCD-Enabled Radioactive Drug Formulation
On September 27, 2024 GE HealthCare announced that the U.S. Food and Drug Administration (FDA) has granted approval of Flyrcado™
Category: CD derivatives
Copolymerized Polymers Based on Cyclodextrins and Cationic Groups Enhance Therapeutic Effect of Rebamipide in the N-Acetylcysteine-Treated Dry Eye Model
β-cyclodextrin polymers were prepared using radical polymerization with co-monomers, 6-deoxy-6-(2-methacryloyloxyethylsuccinamide)-β-cyclodextrin (CD-MSAm) and N,N,N-trimethyl-N-(2-hydroxy-3-metacryloyloxopropyl)-ammonium chloride (QA) to design cyclodextrins suitable for
The revival of cyclodextrins as active pharmaceutical ingredients
Cyclodextrins have long been known as host molecules, a special feature that has led to their widespread use in a
Merck is about to perform post-marketing safety study of HPBCD-containing PREVYMIS™ injection
Merck Sharp and Dohme LLC. has received initial U.S. Approval: 2017 PREVYMIS™ (letermovir) injection, for intravenous use. In the first
Dual-Sensitive CD-Based Nanosystem for Targeted Drug Delivery to Potentiate the Therapeutic Efficacy of Ulcerative Colitis
In view of the overproduction of ROS and overexpression of cationic proteins in the inflammatory colon, the designed nanosystem was
One-pot synthesis of γ-cyclodextrin of high purity from non-food cellulose without the use of complexing agents
Novel synthetic pathways were designed for the synthesis of γ-CD from the non-food feedstock cellulose via an in vitro adenosine
Monomeric, Oligomeric, Polymeric, and Supramolecular Cyclodextrins as Catalysts for Green Chemistry
This review of Prof. Komiyama (University of Tokyo) comprehensively covers recent developments of cyclodextrin-mediated chemical transformations for green chemistry. These
Cyclodextrin polymers containing ionizable and ionic groups: A comprehensive review from classifications and synthesis methods to applications.
Cyclodextrin polymers (CDPs) are a class of polymers that have been extensively used in diverse scientific and technological fields, can
A review on application of sodium sulfobutylether-β-cyclodextrin
According to the authors of this review paper, SBE-β-CD finds widespread application in pharmaceutics as a protective agent and pKa regulator,
Ipecon®: a novel betadex sulfobutylether sodium containing veterinary drug composition
A Russian startup company, Vetstem, located at Skolkovo, Moscow successfully markets an antiviral composition for the treatment of feline infectious