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Author: István Puskás

research chemist
September 22, 2025 CD as API / Pharma applications

7 of 9 patients showed stabilization or improvement: preliminary data from ongoing Phase 3 TransportNPC™ clinical trial

Rafael Holdings, Inc. announced that data from Cyclo Therapeutics’ Phase 3 TransportNPC™ open-label, single-arm sub-study evaluating Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) for Niemann-Pick

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September 15, 2025 Food / Uncategorized

A bagel mimicking the shape of cyclodextrin and also containing cyclodextrin

It is a delightful coincidence that the product’s shape reflects the molecular structure of its key ingredient. In this short

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September 8, 2025 Uncategorized

α-CD Derivatives: Low Efficacy and Ototoxicity in NPC Models

HP-β-CD is currently under clinical investigation for treating Niemann-Pick disease type C (NPC), but its ototoxicity remains problematic. It was

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woman taking cosmetic product from container
September 1, 2025 Cosmetics and toilettry

β-Cyclodextrin/Epichlorohydrin Crosspolymer: a New Cosmetic Ingredient in China

According to data from China’s National Medical Products Administration (NMPA), Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. successfully filed β-Cyclodextrin/Epichlorohydrin Crosspolymer

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August 25, 2025 CD as API / Drug delivery / Pharma applications

A Critical Evaluation of Genuine Cyclodextrin- containing Products in the Post-soviet Market

This study examines suboptimal formulation practices involving cyclodextrins (CDs) in medicinal products across the post-Soviet region, with a focus on

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August 18, 2025 CD as API / CD derivatives / Pharma applications

Results of Phase III clinical trial on efficacy and safety of Adamgammadex

This multicentre, randomised, double-blind, positive-controlled, noninferiority phase III clinical trial aimed to investigate the efficacy and safety of adamagammadex compared

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August 14, 2025 Drug delivery / Pharma applications

Allopregnalonone/SBECD Complex in Clinical Trial for Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in Post Traumatic Stress Disorder

Clinical trial NCT07079761 may help us understand treatable factors that increase risk for chronic or treatment-resistant Post Traumatic Stress Disorder

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July 22, 2025 Cosmetics and toilettry / Non-pharma applications

MANU-KAMU – Dog dental treats with cyclodextrin

Manuka honey is renowned for its health-promoting properties, with well-documented medicinal uses. When combined with α-cyclodextrin it forms a specialized

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July 4, 2025 CD as API / CD derivatives / Drug delivery / Life sciences

Patent applications related to synthesis of heptakis(2,6-di-O-alkyl)-beta-cyclodextrin by CycloLab

45 years ago, Szejtli et al. reported on the synthesis of heptakis(2,6-di-O-methyl)-beta-cyclodextrin using dimethyl sulfate as alkylating agent in a

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July 2, 2025 Food / Non-pharma applications

BCD-for flavor stabilization of beverages: ice tea in Kazakhstan and coffee fortified with flavor

“Maxi-tsai-persik” is a flavored black tea aromatised with peach extract and stabilized with E-459 (beta-cyclodextrin). The product is marketed in

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Recent Posts

  • New book on beta-cyclodextrin and its derivatives
  • Moon, Water and Powdered Alcohol? A Footnote from NASA’s Lunar Life Support Studies
  • Enhancing Sunscreens: HPβCD Improves Ferulic Acid Efficacy
  • Protein Folding with Ionic Liquids and β-CD
  • CD-enhanced drug permeation through biomembranes

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Top Posts

  • Moon, Water and Powdered Alcohol? A Footnote from NASA's Lunar Life Support Studies
  • New book on beta-cyclodextrin and its derivatives
  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • Protein Folding with Ionic Liquids and β-CD
  • How air fresheners work?
  • GRAS status of CD derivatives
  • Novel medicament comprising fosaprepitant/SBECD has been approved.
  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • The monograph of SBECD is official in the European Pharmacopeia
  • Disruption of Lipid Sorting and Endosomal Transport in Cyclodextrin-mediated Cytotoxicity

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