A recent review of Italian researchers emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2 (Covid-19) based on past studies on the attachment of viruses to host cells . Lipid rafts, the cholesterol-rich parts of cell membranes serve as docking places of host cells for the viruses. SARS-COV-2 is a member of a virus family with a lipid envelope that fuses with the host cell through endocytosis, internalizing its components in the cell . Glycoproteins S (spike proteins) of the new coronavirus (SARS-CoV-2) bind to the Angiotensin-Converting Enzyme 2 (ACE2) receptors on human respiratory epithelial cells. In vitro cell models expressing the ACE2 membrane protein have shown that depletion of cholesterol by MeβCD halved the number of bonds with viral S glycoproteins . The molecule not only affects cholesterol levels [4-8] but also expression of the ACE2 receptor. Some studies showed that MeβCD treatment slightly and dose-dependently reduced expression of ACE2 in the cell membrane, also reducing the infectivity of coronaviruses, such as SARS-CoV .
Plant sterols, such as β-sitosterol, reduce the probability of HIV and HBV infectivity .
Cyclodextrins disturb the host cell membrane lipid composition this way reducing the attachment of the virus to the protein receptors, while phytosterols are cholesterol mimics which may link to the virus instead of raft cholesterol.
Both cyclodextrins and phytosterols could have health benefits, such as reduction of blood cholesterol levels, and are used to prevent and reduce the risk of coronary disease, to reduce inflammation, to induce apoptosis in cancer cells and also to treat viral infections. 
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