Unexpected synergistic drug solubilization with γ-CD/phosphoric acid and γ-CD/maleic acid
Dovitinib has been investigated as an anti-tumor drug due to its ability to inhibit multiple receptor tyrosine kinases. Dovitinib free
Tag: solubilization
Promising results of sulfobutylether-β-cyclodextrin based low-melting mixture in the solubilization of steroids
Encapsulation in cyclodextrins (CDs) and solvation in deep eutectic solvents (DESs) are both efficient strategies for the solubilization of poorly
Sulfobutylether-beta-cyclodextrin-enabled antiviral remdesivir: characterization of electrospun- and lyophilized formulations
Veklury™ by Gilead Sciences, Inc., containing antiviral drug, remdesivir (REM) has received emergency authorization in the USA and in Europe
An interesting hypothesis: CD‐sACE2 inclusion compounds to treat COVID‐19
Angiotensin‐converting enzyme 2 (ACE2) has been identified as the main receptors for SARS‐CoV and SARS‐CoV‐2. Soluble ACE2 (sACE2) can bind
Ginkgo terpenoid against COVID-19
Due to the reported high ability of virulence of COVID_19 in recent months, several studies have been conducted to discover
Solubilization and stabilization of beta-acids from hop extract by HPBCD
Hops are the flowers (also called seed cones or strobiles) of the hop plant Humulus lupulus. They are used primarily
Cyclodextrins in soft drinks
CDs are widely studied as suitable components of several beverages either to improve the taste or to enhance the stability
Video-class on the effect of cyclodextrins on drug permeation through membranes
Prof. Thorsteinn Loftsson (University of Iceland) explains in his lecture on the website of CyclonHit project the mechanism how drugs
First cannabidiol product approved by FDA as medication
Cannabis has been used for medicinal purposes for thousands of years. Its active compounds produce pharmacological effects throughout the body,