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Tag: ophthalmic delivery

July 23, 2025 Drug delivery / Pharma applications

Preparation of solid cyclodextrin complexes for ophthalmic active pharmaceutical ingredient delivery

The recently published patent application relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient such as dexamethasone and

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April 16, 2025 CD as API / Drug delivery / Pharma applications

Cyclodextrins: Enhancing Drug Delivery, Solubility and Bioavailability for Modern Therapeutics

This review with 238 references explores the multifaceted roles of cyclodextrins in pharmaceutical formulations, ranging from oral, ophthalmic, parenteral, and

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March 27, 2024 Drug delivery / Pharma applications / Uncategorized

SBECD-BASED THERMOSENSITIVE IN SITU GEL FOR VORICONAZOLE OCULAR DELIVERY AGAINST FUNGAL KERATITIS

Voriconazole/SBECD loaded ophthalmic hydrogel was prepared using Poloxamer 407, a thermosensitive polymer along with hydroxypropylmethylcellulose (HPMCE15) as gelling agents. The

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February 8, 2024 Drug delivery / Pharma applications

Innovative electrospun nepafenac-loaded nanofibers-based ophthalmic inserts

Electrospun nanofibers can be utilized to develop patient-centric ophthalmic formulations with reasonable bioavailability at the targeted site. The current study

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March 24, 2023 Drug delivery

Oculis goes public on the Nasdaq Stock Market

Oculis the Icelandic (now global) ophthalmology company, founded by Thorsteinn Loftsson and Einar Stefánsson, celebrated its public listing on the

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March 6, 2023 Drug delivery / Pharma applications

Cyclodextrin-enabled nepafenac eye drops with improved absorption

Nepafenac is a highly effective NSAID used for treating postoperative ocular inflammation and pain after cataract surgery and its advantage

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July 5, 2022 Drug delivery / Pharma applications

Recent important review articles from Thorsteinn Loftsson’s group about ophthalmic drug delivery

Thorsteinn Loftsson recently published a series of review articles which sums up his advances in ophthalmic drug delivery. This blog

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August 2, 2021 Drug delivery / Pharma applications

Are cyclodextrins safe for intravitreal injections?

Cyclodextrins are excellent excipients for various routes of administration, the ophthalmic delivery is potentially one of the most useful applications

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Recent Posts

  • Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems
  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Events of American Cyclodextrin Consortium
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex

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Top Posts

  • Comparative Study of Nanosuspensions for Acetogenins Delivery
  • Polyphenols' encapsulation in cyclodextrins: An updated systematic literature review
  • Ultrafast-dissolving ocular microneedle patch with voriconazole-cyclodextrin complex
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems
  • Sustained transdermal delivery of insulin-cyclodextrin through the use of chitosan-based microneedle patches
  • Harnessing Organoid Platforms for Nanoparticle Drug Development
  • A review on sodium sulfobutylether-β-cyclodextrin (SBECD)
  • A new multi-compendia modified beta-cyclodextrin, Kleptose® HPB-LB parenteral grade
  • A sugammadex-analogue, per-6-O-carboxyhexyl-thio-gamma-CD (OKL-1111) is a highly potent and universal reversal agent for anticoagulants

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