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Tag: Niemann Pick

March 26, 2020 CD as API / CD derivatives / Pharma applications

Cyclo Therapeutics announces positive safety profile of its drug Trappsol Cyclo

Cyclo Therapeutics, Inc., a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of Niemann-Pick Disease Type C (NPC)

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February 6, 2020 CD as API / CD derivatives / Pharma applications / Uncategorized

Cyclo Therapeutics Presents Clinical Trial Data on Niemann-Pick Type C Disease

Cyclo Therapeutics, Inc. a clinical-stage biotechnology company that develops cyclodextrin-based products for the treatment of Niemann-Pick Disease Type C (NPC)

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June 6, 2019 CD as API / CD derivatives / E-ducation

Carbohydrate drugs (Part 5) (Oligosaccharides, cyclodextrins)

First let’s talk about one of the biggest achievements in the history of cyclodextrin research: Sugammadex. Sugammadex (SGM) (BridionTM) (1a)

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February 20, 2019 CD as API / CD derivatives

CTD Reports Initial Data for Two Clinical Trials of Trappsol® Cyclo™

CTD Holdings, Inc., a clinical stage biotechnology company that develops cyclodextrin-based products for the treatment of disease with unmet medical

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September 22, 2018 CD as API / Pharma applications

Therapeutic potential for cyclodextrin‐based macromolecular systems in NPC

A paper has just come out in Macromolecular Rapid Communications highlighting the potential benefits of cyclodextrin-based macromolecular systems as cholesterol-mopping

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September 13, 2018 CD as API / Pharma applications

HPBCD was tested for revealing the symptoms of Cockayne syndrome in mouse model: a surprise

Cockayne syndrome is a hereditary form of premature aging caused by a gene mutation. The disease affects more organs including

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August 23, 2018 CD as API / Pharma applications

Advancements of CD analysis in Niemann-Pick C

Clearly, understanding the mechanism of action for cyclodextrins and consequently finding the most appropriate canditate for the treatment of Niemann

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July 31, 2018 CD as API / Pharma applications

HPBCD can cross the Brain-Blood Barrier

Matencio et al. reported in their recent paper that 92.8% of HPBCD administered intrathecally to a child suffering from Niemann

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  • Pharmacokinetic studies of hyperoside-2-hydroxypropyl-β-cyclodextrin inclusion complex and ameliorated colitis in mice
  • Aggregation versus inclusion complexes to solubilize drugs with cyclodextrins. A case study using sulfobutylether-β-cyclodextrins and remdesivir

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