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Tag: Niemann Pick Disease

September 21, 2023 CD as API / CD derivatives / Pharma applications / Uncategorized

Different solubilizing ability of cyclodextrin derivatives for cholesterol in Niemann–Pick disease type C treatment

Cyclodextrins (CDs), the therapeutic candidates for Niemann–Pick disease type C (NPC), function dually as a shuttle and sink that catalytically

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July 25, 2023 CD as API / Pharma applications

Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) in Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial

Niemann-Pick disease type C (NPC) is a rare, fatal, pan-ethnic, autosomal recessive lysosomal storage disease characterized by progressive major organ

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July 21, 2023 CD as API / Pharma applications

Remembering Dr. David Begley

With immense sadness we have to announce that an outstanding Scientist, Dr. David Begley passed away on Thursday 6th July

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April 21, 2023 CD as API / Pharma applications

The review article ‘Molecular Mind Games’ describes the latest developments in cyclodextrin research for the treatment of brain disorders

The human brain is a complex and intricate network of cells and molecules that control every aspect of our behaviour

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April 14, 2023 CD as API / CD derivatives / Pharma applications

Grafting of Cyclodextrin to Theranostic Nanoparticles Improves Blood-Brain Barrier Model Crossing

Core–shell superparamagnetic iron oxide nanoparticles hold great promise as a theranostic platform in biological systems. Herein, we report the biological

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December 1, 2022 CD as API / Pharma applications

Cyclodextrins: Only Pharmaceutical Excipients or Full-Fledged Drug Candidates?

In this review, based on 250 references, the general chemical principles of direct cyclodextrin–protein interactions are summarized and highlighted, through

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October 11, 2022 CD as API / Pharma applications

Inclusion Solves Insolubility ―Translational Research Cycle from Bedside to Bench and Bench to Bedside for Drug Development Targeting Niemann-Pick Disease Type C

Cyclodextrins (CDs) are used not only as pharmaceutical excipients but also as active pharmaceutical ingredients. CDs can act as artificial

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October 5, 2022 CD as API / CD derivatives

Monosubstituted Maltosyl Cyclodextrins for the Potential Treatment of NPC

Niemann-Pick type C is a sever lysosomal storage disease, commonly refereed as ‘children’s Alzheimer’. There is no cure for it

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August 3, 2022 CD as API / Pharma applications

HPaCD against Alzheimer Disease

HP-beta-cyclodextrin (HPbCD) is currently in clinical trials against Niemann-Pick Disease Type C (NPC) and Alzheimer’s Disease (AD) and these trials

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July 12, 2022 CD as API / Events / Pharma applications

Cyclo Therapeutics to Present at the 2022 NPC Patient and Family Conference Hosted by the Australian NPC Disease Foundation

Presentation by Professor Caroline Hastings, MD, Chair of the Phase 3 Trappsol® Cyclo™ Program Steering Committee and the Global Principal Investigator

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Recent Posts

  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Innovative Titanium Coatings for Enhanced Dental Implants
  • Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers
  • FermenGIN: γ-Cyclodextrin Takes the Bitterness Out of Bioconverted Red Ginseng
  • New book on beta-cyclodextrin and its derivatives

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Top Posts

  • Innovative Titanium Coatings for Enhanced Dental Implants
  • Cyclodextrin-Branched Polymer Releasing Nitric Oxide with Fluorescent Self-Reporting and Its Combination with Doxorubicin
  • Bio-inks for skin regeneration: phase-adaptive design, multifunctional platforms, and 4D bioprinting frontiers
  • New cyclodextrin with orphan drug designation: SBECD
  • Cyclodextrin dimers to treat atherosclerotic plaques by targeting various forms of cholesterol
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Old but Gold (literally)!
  • Lanosterol eye drops for cataract treatment
  • Selecting a non-interacting buffer for α-cyclodextrin containing solutions
  • International Summer School on Cyclodextrins

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