Hydroxypropyl-Beta Cyclodextrin Barrier Prevents Respiratory Viral Infections
The emergence and mutation of pathogenic viruses have been occurring at an unprecedented rate in recent decades. The coronavirus disease
Tag: influenza
Safety, Immunogenicity of a Novel HPBCD-Adjuvanted Influenza Vaccine
A novel quadrivalent seasonal influenza vaccine (FluCyd-vac) adjuvanted with hydroxypropropyl-b-cyclodextrin (HP-β-CD) was found to be safe and immunogenic despite containing
New class of anti-influenza macromolecules based on beta-cyclodextrin
A new class of anti-influenza macromolecules were synthesized based on a cyclodextrin to target conserved viral domains irreversibly. 6’ sialyl-N-acetyllactosamine
Carbohydrate drugs (Part 1)
As we know, cyclodextrins are composed of α-D-glucopyranose units. Among pharmaceuticals there are several other carbohydrate type drugs. In this
A HPBCD solubilized novel fusion inhibitor of influenza virus was found orally active in mice
A group of researchers employed by different subsidiaries of Janssen Research & Development, Scripps Research Institute, Department of Epidemiology, as well
A clinical phase1 study of Hydroxypropyl-beta-cyclodextrin (HPBCD)-adjuvanted influenza split vaccine
Osaka University Hospital with the support of Daichii Sankyo is sponsoring a clinical trial on a vaccine against influenza virus.