HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
Several North-American Universities worked together to find hydroxzpropyl-alpha-cyclodextrin(HPaCD) for the treatment of Krabbe disease. The deficiency of β-galactosylceramidase causes a
Tag: CNS
Cholesterol in the CNS: functions, recycling and remyelination
The central nervous system ( CNS) is increasingly recognized as a cholesterol-rich organ. While the brain accounts for approximately 5%
Possible treatment of brain tuberculosis by methyl-β-cyclodextrin–assisted trans-nasal delivery of anti-tuberculosis drugs
Tuberculosis (TB) is prevalent worldwide. One of the most life-threatening manifestation of extrapulmonary tuberculosis is the involvement of central nervous
Antinociceptive effect of isopulegol and its complex in cyclodextrin
Isopulegol, an intermediate of the production of menthol, and widely used for its flavoring and anesthetic properties. Isopulegol, a terpene
Central nervous system delivery of molecules across the blood-brain barrier
Therapies targeting neurological conditions such as Alzheimer’s or Parkinson’s diseases are hampered by the presence of the blood-brain barrier (BBB).
Cyclolab and EpiPharma Form Joint Venture company Targetrin Therapeutics to Develop and Commercialize novel conjugated Cyclodextrin – Peptide drugs
Cyclolab, the oldest, world renowned cyclodextrin research, development and manufacturing company, and EpiPharma, a bio-pharmaceutical services and peptide drug development
Axsome Therapeutics Announces Acceleration of MOMENTUM Phase 3 Trial of AXS-07 in Migraine
Axsome Therapeutics, Inc., a clinical-stage biopharmaceutical company developing novel therapies for the management of central nervous system (CNS) disorders, today
Cyclodextrins as theranostics
The application of cyclodextrins as excipients is wellspread, common knowledge worldwide. Their application as APIs is getting huge publicity, developments