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Tag: Clinical trial

September 22, 2025 CD as API / Pharma applications

7 of 9 patients showed stabilization or improvement: preliminary data from ongoing Phase 3 TransportNPC™ clinical trial

Rafael Holdings, Inc. announced that data from Cyclo Therapeutics’ Phase 3 TransportNPC™ open-label, single-arm sub-study evaluating Trappsol® Cyclo™ (hydroxypropyl-beta-cyclodextrin) for Niemann-Pick

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September 16, 2025 CD as API / Drug delivery / Pharma applications

Cyclodextrin-based therapeutics delivery systems: A review of current clinical trials

Cyclodextrins (CDs) and their polymers are gaining momentum as advanced drug delivery systems. A recent review (https://www.sciencedirect.com/science/article/pii/S2590257125000203) highlights their progress

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January 14, 2025 CD as API / Pharma applications

Cyclodextrin derivative developed by Cyclarity in clinical trial

Cyclarity Therapeutics is pleased to announce regulatory approval to begin its first-in-human clinical trial. The trial will be conducted at CMAX,

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December 11, 2024 CD as API / Pharma applications

Alzheimer’s disease drug development pipeline: 2024

New therapies to prevent or delay the onset of symptoms, slow progression, or improve cognitive and behavioral symptoms of Alzheimer’s

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white hospital beds
September 25, 2024 CD derivatives / Drug delivery / Pharma applications

Merck is about to perform post-marketing safety study of HPBCD-containing PREVYMIS™ injection

Merck Sharp and Dohme LLC. has received initial U.S. Approval: 2017 PREVYMIS™ (letermovir) injection, for intravenous use. In the first

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August 27, 2024 CD as API / Pharma applications

Rafael Holdings and Cyclo Therapeutics merge to advance Niemann-Pick drug as FDA rival decision nears

Rafael Holdings and Cyclo Therapeutics on Thursday announced a merger agreement as they look to spur development of their Niemann-Pick

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February 12, 2024 Food / Non-pharma applications

Gamma-cyclodextrin in herbal drinks with anti-aging and uric acid lowering effect

A randomized, double-blind controlled trial (NCT05986799) sponsored by Amway (China) was planned to start in August 2023 to study whether

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July 26, 2023 CD as API / Pharma applications

The Use of Sugammadex as Rescue Therapy Following Inadequate Reversal With Neostigmine – Clinical trial

Neuromuscular blocking agents (NMBAs) are commonly used in the practice of anesthesiology for skeletal muscle relaxation to facilitate tracheal intubation,

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July 25, 2023 CD as API / Pharma applications

Long-term administration of intravenous Trappsol® Cyclo™ (HP-β-CD) in Niemann-Pick disease type C1: Results of an international 48-week Phase I/II trial

Niemann-Pick disease type C (NPC) is a rare, fatal, pan-ethnic, autosomal recessive lysosomal storage disease characterized by progressive major organ

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February 13, 2023 Drug delivery / Pharma applications

Midazolam/γ-cyclodextrin Premedication in Pediatric Anesthesia

ADV6209, a new formulation of midazolam with the addition of γ-cyclodextrin for oral use, has recently been licensed as the

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Recent Posts

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  • First EMA regulation on the residues of betadex sulfobutylether sodium in foodstuffs of animal
  • From an Idea to a Journey: My Path Toward Treating Gout and Hyperuricemia With Cyclodextrins
  • Beta-cyclodextrin/salicylic acid complex in pads for wart treatment
  • Paper strips with β-Cyclodextrin-functionalized silver nanoparticles as a visual probe for selective tetrahydrocannabinol detection

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Top Posts

  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • First EMA regulation on the residues of betadex sulfobutylether sodium in foodstuffs of animal
  • JIC Venture Growth Investments Invests in Beren Therapeutics P.B.C. to Advance Innovative, Cyclodextrin-based Therapeutics
  • Cyclodextrin attenuates atherosclerosis by diminishing gasdermin D (GSDMD)-mediated pyroptosis
  • From an Idea to a Journey: My Path Toward Treating Gout and Hyperuricemia With Cyclodextrins
  • High-swelling cyclodextrin polymer for sustainable water purification
  • Cyclodextrins for UV Protection in Food, Beverages, and Agricultural Products
  • Alpha-Cyclodextrin Containing Barista Oat Drink
  • Eva Pharma, DRL, Biocon and Zydus Cadila added to Voluntary Licensing Agreements for Remdesivir

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