An antibody–supermolecule conjugate for cancer chemotherapy
In this study, antibody–supermolecule conjugates, consisting of a tumor-specific antibody and acid-labile polyrotaxane containing methylated b-cyclodextrin (Me-PRX), were designed to
Tag: Cancer therapy
Nitric oxide-releasing cyclodextrins as biodegradable antibacterial scaffolds: a patent evaluation of US2019343869(A1)
Introduction: Antimicrobial resistance is one of the major scourges for healthcare worldwide, therefore novel investigational approaches are needed to potentiate and
FDA Approves New KYPROLIS® (SBECD-enabled carfilzomib) Combination Regimen With DARZALEX® (daratumumab) And Dexamethasone
Approval Based on the CANDOR and EQUULEUS Studies in Patients With Relapsed/Refractory Multiple Myeloma Amgen today announced the U.S. Food and
Biodegradable β ‐Cyclodextrin Conjugated Gelatin Methacryloyl Microneedle for Delivery of Water‐Insoluble Drug
Transdermal drug delivery offers advantages over nonparenteral routes such as bypassing first-pass metabolism and facile administration. Mammalian skin, however, functions
Cyclodextrin as a magic switch in covalent and non-covalent anticancer drug release systems
This article reviews the controlled release of current anticancer drugs based on cyclodextrins as a “flexible switch”, and discusses the
Supreme delivery effect of β-cyclodextrin for hypoxic cancer cells recognized in 2019 Nobel prize laureate’s lab
2019 Nobel prize in Physiology or Medicine will be awarded to William G. Kaelin Jr., Sir Peter J. Ratcliffe and
Folate-Decorated Amphiphilic Cyclodextrins as Cell-Targeted Nanophototherapeutics
The group of Prof. Mazzaglia published on a ternary nanoassembly (SAP) composed of nonionic amphiphilic β-cyclodextrins (amphiphilic CD) incorporating pheophorbide
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics (edited by Prashant Kesharwani, Kishore Paknikar and Virendra Gajbhiye) and published by
International Congress and Exhibition on Pharmacy
The International Congress and Exhibition on Pharmacy will be held on 15–16 August, 2019, in Prague, Czech Republic. The motto
Methyl-β-cyclodextrin, an actin depolymerizer augments the antiproliferative potential of microtubule-targeting agents
The effect of Methyl BCD (RAMEB) on cytoskeleton was studied. It was found that disassembling the actin network did not