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Tag: bioavailability

February 9, 2022 CD as API / Drug delivery / Pharma applications

Versatile Nasal Application of Cyclodextrins: Excipients and/or Actives?

The use of CDs in nasal formulations allowed obtaining versatile drug delivery systems intended for local and systemic effects, as

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January 27, 2022 Drug delivery / Pharma applications

Fat-Soluble Vitamin Supplementation Using Liposomes, Cyclodextrins, or Medium-Chain Triglycerides in Cystic Fibrosis: A Randomized Controlled Trial

Fat-soluble vitamin deficiency remains a challenge in cystic fibrosis (CF), chronic pancreatitis, and biliary atresia. Liposomes and cyclodextrins can enhance

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December 7, 2021 Drug delivery / Pharma applications

γ-Cyclodextrin-based polypseudorotaxane hydrogels for ophthalmic delivery of flurbiprofen to treat anterior uveitis

Anterior uveitis is a sight-threatening inflammation inside the eyes. Conventional eye drops for anti-inflammatory therapy need to be administered frequently

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May 7, 2021 Food / Non-pharma applications / Uncategorized

CAVACURMIN®: Study Reveals Increased Metabolic Bioavailability of Tetrahydrocurcumin

A study recently published in the Journal of Functional Foods shows that ingestion of the curcumin-cyclodextrin complex CAVACURMIN® leads to an

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March 3, 2021 Drug delivery / Pharma applications

Improving Bioavailability & Solubility

Drug Development & delivery published on the virtual 2020 Global Drug Bioavailability Enhancement Summit, which this past December showcased novel

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June 9, 2020 Agriculture / CD derivatives

Use of cyclodextrins as agrochemical delivery system

ADAMA MAKHTESHIM LTD. (Israel) filed a PCT patent application (WO2020084572) that was recently published. The invention relates to preparation and use

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October 17, 2019 Food

WACKER Confers Innovation Award for Development of CAVACURMIN®

Munich-based chemical group WACKER has conferred the Alexander Wacker Innovation Award on Rachela Mohr and Dr. Helmut Reuscher for developing

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March 25, 2019 Pharma applications

Phase I clinical trial posted on Relative Bioavailability of CE-Iohexol (Captisol-enabled™ Iohexol) Injection

This study is designed to compare the bioavailability of the test Product (CE-Iohexol Injection) and the reference product Iohexol Injection

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February 7, 2019 Environmental / Non-pharma applications

CDs in biodegradation-based soil remediation under aerobic conditions

The non-toxic, biodegradable cyclodextrins (CDs) can solubilize poorly soluble organic contaminants such as PAHs, PCBs, chlorinated solvents, etc. via molecular

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December 18, 2018 Drug delivery / Pharma applications

A “Ship-in-a-Bottle” strategy to enhance solubility and bioavailability

Metal-organic frameworks (MOFs) consisting of γ-cyclodextrin and potassium were used to incorporate folic acid clusters. The molar ratio of folic

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  • Cyclodextrin improve the composition of dairy products, an example in food industry
  • International Conference on Bioinspiration and Biobased​ Materials
  • Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin
  • Have you ever washed your hands with HPBCD-containing soap? Check it out!

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Top Posts

  • Cholesterol/β-cyclodextrin complexation revisited by combined experimental and computational approaches
  • Cyclodextrin improve the composition of dairy products, an example in food industry
  • Have you ever washed your hands with HPBCD-containing soap? Check it out!
  • Regorafenib@mannose-γ-cyclodextrin channel-type nanoparticles for colorectal cancer therapy
  • Self-Inclusion and Dissociation of a Bridging β‑Cyclodextrin Triplet
  • Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
  • GRAS status of CD derivatives
  • SBECD partly inhibits the renal excretion of anionic drugs
  • How air fresheners work?
  • Program of International Cyclodextrin Symposium

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