Final Results of NIAID’s Trial Expand Clinical Benefits of Veklury® (remdesivir) for the Treatment of COVID-19
— Final Day 29 Data Show Superior Efficacy of Veklury Compared with Placebo in Hospitalized Patients Receiving Standard of Care
Category: Drug delivery
Ivermectin against COVID-19
Ivermectin is a medication used to treat a number of parasite infections. Chemically, this compound and derivatives are macrocyclic lactones
Inclusion complex of chrysin with sulfobutyl ether-β-cyclodextrin
The work of Kulkarni and Belgamvar [1] demonstrates the impact of sulfobutyl ether-β-cyclodextrin (SBE-β-CD) complexation on the solubility, dissolution and
UofA lab uncovers new mechanism of action against SARS-CoV-2 by antiviral drug remdesivir
News Release on 23-Sep-2020 on Eurokalert Researchers at the University of Alberta have discovered a novel, second mechanism of action
CD-related papers in Scientific Reports
Scientific reports (Nature) has published 10 cyclodextrin-related papers in the last 3 months. Here is a selection: Parvez, S., Yadagiri,
Highly Enhanced Curcumin Delivery Applying Association Type Nanostructures of Block Copolymers, Cyclodextrins and Polycyclodextrins
Self-association type systems of polyethylene oxide-polypropylene oxide-polyethylene oxide block copolymers (Pluronic) were applied to enhance the aqueous solubility of curcumin.
Use of cyclodextrin or its complexes as a potential treatment against the 2019 novel coronavirus
Coronavirus 2 is a member of a virus family with lipid envelope that fuses with host cell through endocytosis, internalizing
Novel dexamethasone formulation shows efficacy and safety with once-daily use
Eric D. Donnenfeld, a consultant to Oculis reported for Ophthalmology Times on the results of a phase 2 trial: dexamethasone
Non-parenteral formulation of Remdesivir for Covid-19 treatment
Remdesivir exhibits in vitro activity against SARS-CoV-2 and was granted approval for Emergency Use. To maximize delivery to the lungs,
Nitric oxide in the treatment of coronavirus disease (COVID-19)
„Inhaled nitric oxide dilates or widens arteries to allow more blood to flow through the lungs. It also relaxes the