Twenty years of research on cyclodextrin conjugates with PAMAM dendrimers
Cyclodextrin (CD) conjugates with starburst polyamidoamine (PAMAM) dendrimer (CDEs), as a new type of polymer-based carriers, were first published in
Category: CD derivatives
Polypeptide-Shelled Cyclodextrin-Containers for Intracellular Delivery of Membrane-Impermeable Cargo
The transport of membrane impermeable compounds into cells is a prerequisite for the efficient cellular delivery of hydrophilic and amphiphilic
Adjusting the Structure of β-cyclodextrin to Improve Complexation of Anthraquinone-derived Drugs
A nice example for the tailor-made CD derivatives: CD derivatives containing aromatic triazole ring were studied as potential carriers of
Results of the survey at the CycloLab’s webinar on “Cyclodextrins as active ingredients in the 21st century”
During the webinar of CycloLab “Cyclodextrins as active ingredients in the 21st century” held on Oct. 11, 2021, the participants
Alveron Pharma raises a further EUR 3.9 million to progress first in class cyclodextrin drug
Alveron Pharma BV (Nijmegen, The Netherlands) has raised a further EUR 3.9 million to fund the continued development of OKL-1111,
CDs as Dominant Chiral Selective Agents in the Capillary Separation Techniques
This review paper shows the dominant role of the cyclodextrins in the chiral separations using capillary columns (GC, SFC, CE).
Underdog Closes $10M Financing Round – the next cyclodextrin can be developed further as active
Underdog Pharmaceuticals, a key investment of Michael Greve’s rejuvenation biotech VC Kizoo, has closed a $10 million round of capital.
Meet the Experts: Cyclodextrins as active ingredients in the 21st century – Webinar of CycloLab
After the great success of the webinar held in May, 2021 a next webinar organized by CycloLab will be held
Novel β-cyclodextrin Polyurethane Materials with Antibiotic Activity
Novel quaternary ammonium salt functionalized β-cyclodextrin polyurethane (QAS-β-CDPU) microparticles were successfully constructed . By adjusting the proportion of the chlorine-containing
Harvard scientists discover the prophylactic effect of SBECD solubilized amodiaquine against SARS-CoV2 infection
Amodiaquine is a commonly used medicament for the treatment of malarial infections. It is a 4-aminoquinoline compound similar to chloroquine