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Category: CD derivatives

June 2, 2022 CD derivatives / Gene delivery / Pharma applications

Tetraethylenepentamine-Coated β Cyclodextrin Nanoparticles for Dual DNA and siRNA Delivery

Tetraethylenepentamine-coated β-cyclodextrin (TEPA-BCD) nanoparticles were synthesized, characterized, and evaluated for targeted cell delivery of plasmid DNA and siRNA. The cationic

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May 31, 2022 Analysis / CD derivatives / Non-pharma applications

Enhanced Chiral Recognition Abilities of Cyclodextrin Covalent Organic Frameworks via Chiral/Achiral Functional Modification

β-Cyclodextrin covalent organic frameworks (β-CD COFs) show great potential in enantioseparation due to their uniformly distributed chiral recognition sites and

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May 26, 2022 CD derivatives / Drug delivery / Pharma applications

Update: FDA approves HPBCD-enabled tecovirimat against pox virus

As reported earlier Siga Technologies filed a patent application in the USA describing cyclodextrin solubilized tecovirimat (ST-246). Tecovirimat has low

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May 26, 2022 CD derivatives / Drug delivery / Pharma applications

Life cycle of Tecovirimat authorized to treat human monkeypox infection in EU has been extended by reformulation with HPBCD by the originator Siga Technologies.

Tecovirimat SIGA (marketed under the trade name TPOXX® in USA) is an oral medicine to treat smallpox, monkeypox and cowpox,

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May 26, 2022 CD derivatives

pH-Responsive templates modulate the dynamic enzymatic synthesis of cyclodextrins

Product selection in the dynamic enzymatic synthesis of cyclodextrins can be controlled by changing the pH. Using cyclodextrin glucanotransferase to

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May 4, 2022 CD as API / CD derivatives / Drug delivery / Pharma applications

Implementation of water-soluble cyclodextrin-based polymers in biomedical applications: how far are we?

Cyclodextrin-based polymers can be prepared starting from the naturally occurring monomers following green and low-cost procedures. They can be selectively

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April 21, 2022 CD derivatives

Superdimer guanidino-γ-cyclodextrin

Octakis-6-guadinidino-γ-cyclodextrin (gguan) hydrochloride in the presence of phosphates crystallises from aqueous solution in the unprecedented form of a superdimer (dimer-within-a-dimer).

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April 20, 2022 CD derivatives / Drug delivery / Pharma applications

Dramatically Increased Binding Constant of Water-Soluble Cyclodextrin Hyperbranched Polymers

The polymerization of cyclodextrin (CD) with epichlorohydrin (ECH) dramatically increases the binding constant of CD to vanillin, from 55 to

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April 19, 2022 CD derivatives

Two ways for manufacturing CD fibres

In this work [1], (2-Hydroxypropyl)- β-cyclodextrin) fibres were successfully produced with water, as the “green” solvent with pressurised gyration and electrospinning,

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April 6, 2022 CD derivatives

Cyclodextrin-Oligocaprolactone Derivatives-Synthesis and Advanced Structural Characterization by MALDI Mass Spectrometry

The β-cyclodextrin derivatization with short oligoester chains, through convenient synthesis methods, leads to highly water-soluble and biodegradable compounds. Cyclodextrins have

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Recent Posts

  • Cyclodextrin keeps the head on non-alcoholic beer
  • Scientific Program of ICS22 India
  • Cyclodextrins may help a therapeutic agent en route to the brain
  • Enhancing Foamability of Oat Milk with In Situ Generated Cyclodextrins
  • 1-Methylcyclopropene: from the CD cavity to the apple tree

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Top Posts

  • Cyclodextrin keeps the head on non-alcoholic beer
  • Sulfated β-Cyclodextrin-Mediated Antimicrobial Peptide Nanoparticles for Alkaloid Encapsulation
  • Scientific Program of ICS22 India
  • α-cyclodextrin-based polyrotaxanes for tissue engineering
  • Three generations of thiolated cyclodextrins: A direct comparison of their mucus permeating and mucoadhesive properties
  • 45 years of paracetamol (acetaminophen)–beta-cyclodextrin complex history - now used in versatile pharmaceuticals
  • Rigid crosslink improves the surface area and porosity of β-cyclodextrin beads for enhanced adsorption of flavonoids
  • International Conference on Nanotechnology (Nanotech-2022)
  • Nasal delivery with beta-cyclodextrin is approved; a short story of Baqsimi
  • Cyclodextrin Complexes: A New Hope Against Atherosclerosis

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