In this work [1], (2-Hydroxypropyl)- β-cyclodextrin) fibres were successfully produced with water, as the “green” solvent with pressurised gyration and electrospinning, without using a carrier polymer. The average fibre diameter of the pressurised gyration produced fibres ranged between 5.5 to 5.8 μm, whilst the average fibre diameter of the electrospun fibres ranged between only 183 – 305 nm. These findings show the thinnest diameter of pure cyclodextrin achieved in the literature. Both techniques had specific advantages, such as electrospinning being able to produce nanofibres, whilst pressurized gyration had productivity of over 1.5 grams per minute. Here we present a pioneering study into the production of cyclodextrin-only fibres with two different fibre production techniques and the creation of a cyclodextrin-super-mat that combines both types of fibres.
[1] A Kelly, J Ahmed, M Edirisinghe (2022) Manufacturing Cyclodextrin Fibres using Water. Macromolecular Materials and Engineering. https://doi.org/10.1002/mame.202100891
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Phoebe L. Heseltine, Jubair Ahmed, Mohan Edirisinghe (2018) Developments in Pressurized Gyration for the Mass Production of Polymeric Fibers. Macromolecular Materials and Engineering 303, 1800218
https://doi.org/10.1002/mame.201800218