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Author: István Puskás

research chemist
November 12, 2021 Life sciences

Phospholipid/methyl-ACD complex enhancing donor blood stability

Inventors Amir Farnoud and Amid Vahedi (Ohio University, US) have filed a patent application entitled “Methods for extending the shelf-life

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November 11, 2021 Life sciences / Pharma applications

Role of HPBCD in development of Pfizer’s novel COVID-19 oral antiviral treatment candidate

Pfizer’s breakthrough drug candidate PF-07321332 used in combination with ritonavir was poven to successfully reduce the risk of hospitalization and

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October 1, 2021 Drug delivery / Pharma applications

Memorial Sloan Kettering Cancer Center: Potential treatment of COVID-19 using inhalable camostat/nafamostat formulated with HPBCD or SBECD

Memorial Sloan Kettering Cancer Center (MSKCC) has filed a patent application on an inhalational therapeutic composition of camostat solubilized by

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September 29, 2021 Analysis / CD derivatives / Non-pharma applications

CDs as Dominant Chiral Selective Agents in the Capillary Separation Techniques

This review paper shows the dominant role of the cyclodextrins in the chiral separations using capillary columns (GC, SFC, CE).

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syringe and pills on blue background
September 17, 2021 CD derivatives / Drug delivery

Harvard scientists discover the prophylactic effect of SBECD solubilized amodiaquine against SARS-CoV2 infection

Amodiaquine is a commonly used medicament for the treatment of malarial infections. It is a 4-aminoquinoline compound similar to chloroquine

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September 14, 2021 Analysis / CD derivatives

Single Isomer N-Heterocyclic Cyclodextrin Derivatives as Chiral Selectors in Capillary Electrophoresis

In order to better understand the chiral recognition mechanisms of positively charged cyclodextrin (CD) derivatives, the synthesis, the pKa determination by 1H

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August 6, 2021 Pharma applications

Cyclodextrin-containing hard capsule of improved mechanical strength

CAPSUGEL JAPAN INC filed a patent application which has been published recently (WO2021145296). The subject matter is a hard capsule improved

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close up photo of yellow orange rose
July 30, 2021 Non-pharma applications / Other industrial use

Cyclodextrins in 3D and 4D printing

4D printing? Yes! 4D printing is a process through which a 3D printed object transforms itself into another structure over the influence

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July 21, 2021 Drug delivery / Pharma applications / Uncategorized

Intraoral/intranasal niclosamide/HPBCD formulation for treatment of COVID-19

A recently published patent of Union Therapeutics, Denmark (US11045434) (granted extremely rapidly by USPTO within 8 months from filing date)

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June 9, 2021 Events

37th Cyclodextrin Symposium, Japan: moves online

The 37th Cyclodextrin Symposium, Japan, which has been postponed, will be held online on September 2nd (Thursday) and 3rd (Friday). Details

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Recent Posts

  • Special Issue “Cyclodextrin-Functionalized Materials for Drug Delivery, Pharmaceutical and Medical Applications”
  • Cyclodextrin-Based Oral Solution of Ursodeoxycholic Acid Using a Ready-to-Use Vehicle
  • Cyclodextrin-based electrochemical sensors for PFAS detection
  • FDA: Inclusion complex of a GRAS guest and a GRAS host is also GRAS
  • HPBCD for the treatment of irreversible white matter injury

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Top Posts

  • Special Issue "Cyclodextrin-Functionalized Materials for Drug Delivery, Pharmaceutical and Medical Applications"
  • Cyclodextrin-Based Oral Solution of Ursodeoxycholic Acid Using a Ready-to-Use Vehicle
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • 4th International Biotechnology Congress 2020
  • Cholesteryl Cyclodextrin for Enhanced Delivery of Doxorubicin and 5-Fluorouracil
  • Call for Book Chapters: Cyclodextrin Systems for Green Hydrogen Production
  • FDA: Inclusion complex of a GRAS guest and a GRAS host is also GRAS
  • Call for Chapters: Cyclodextrins in Nutraceuticals 
  • Early peek at data on Gilead coronavirus drug suggests patients are responding to treatment
  • Nystatin:β-cyclodextrin inclusion complexes - revisited

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