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Author: István Puskás

research chemist
May 26, 2022 CD derivatives / Drug delivery / Pharma applications

Life cycle of Tecovirimat authorized to treat human monkeypox infection in EU has been extended by reformulation with HPBCD by the originator Siga Technologies.

Tecovirimat SIGA (marketed under the trade name TPOXX® in USA) is an oral medicine to treat smallpox, monkeypox and cowpox,

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May 16, 2022 Cosmetics and toilettry / Non-pharma applications

Have you ever washed your hands with HPBCD-containing soap? Check it out!

Dettol is a brand of cleaning supplies, disinfectant and antiseptic, introduced in 1932. The manufacturer is owned by the British

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May 9, 2022 Food / Non-pharma applications

Alpha-cyclodextrin powder for ice cream

Alpha-cyclodextrin powder is marketed for stabilization of emulsions like ice creams and sorbets. The recommended dose is 0,01%-0,2%. The fine

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April 21, 2022 CD derivatives

Superdimer guanidino-γ-cyclodextrin

Octakis-6-guadinidino-γ-cyclodextrin (gguan) hydrochloride in the presence of phosphates crystallises from aqueous solution in the unprecedented form of a superdimer (dimer-within-a-dimer).

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March 31, 2022 Non-pharma applications / Other industrial use

Novel thermocell based on cyclodextrin host–guest interactions.

The use of thermoelectric materials was discovered by Thomas Johann Seebeck (as early as in 1821) for waste-heat recovery, refrigeration

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March 24, 2022 CD as API / CD derivatives / Pharma applications / Supramolecular systems

Antidote-like effect of SBECD of plant neurotoxin veratridine on neuro-2a cell viability

A research team consisting of scientists located in Spain and Denmark have successfully proven that the formation of inclusion complexes

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March 1, 2022 Analysis / Life sciences / Non-pharma applications

Beta-cyclodextrin filled analytical column will be carried again to Mars (by Rosalind Franklin rover).

In the near future ESA’s ExoMars mission plans to deliver the Rosalind Franklin rover onthe surface of Mars [1]. This

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February 24, 2022 CD derivatives

Magic cyclodextrins turn blue on rubbing: mechanochromism

Prof. Aoki wrote this short summary for our blog on their unique achievement: In this study, we have used cyclodextrins

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yellow green and red medication pill blister pack
February 4, 2022 CD derivatives / Drug delivery / Pharma applications

SPORANOX vs. SCEMBLIX combat: HPBCD is the referee?

SCEMBLIX (Asciminib) is indicated for the treatment of adult patients with chronic myeloid leukaemia previously treated with two or more

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January 17, 2022 CD derivatives / Drug delivery

HPBCD solubilized drug candidate is effective to treat prostate tumor – as published in Nature

Scientists at the University of Michigan have described a key nexus that several cancer-promoting genes depend on to drive prostate

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Recent Posts

  • New book on beta-cyclodextrin and its derivatives
  • Moon, Water and Powdered Alcohol? A Footnote from NASA’s Lunar Life Support Studies
  • Enhancing Sunscreens: HPβCD Improves Ferulic Acid Efficacy
  • Protein Folding with Ionic Liquids and β-CD
  • CD-enhanced drug permeation through biomembranes

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Top Posts

  • Moon, Water and Powdered Alcohol? A Footnote from NASA's Lunar Life Support Studies
  • New book on beta-cyclodextrin and its derivatives
  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • Protein Folding with Ionic Liquids and β-CD
  • How air fresheners work?
  • GRAS status of CD derivatives
  • Novel medicament comprising fosaprepitant/SBECD has been approved.
  • 22nd International Cyclodextrin Symposium (ICS-22) in India
  • The monograph of SBECD is official in the European Pharmacopeia
  • Scientific Program of ICS22 India

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