Posted by Special Issue entitled “The Role of Carbohydrate in Pharmaceuticals, Vaccines and Delivery Systems”, in
Pharmaceutics (*IF 6.525, 5-Year IF 7.227, PubMed, Q1*)
This Special Issue of Pharmaceutics has been dedicated to the role of carbohydrates as therapeutic agents, vaccines, and delivery systems. Recent trends in carbohydrate chemistry are indicating their importance in medicinal chemistry in terms of key players for the treatment of a wide range of diseases, including immuno-oncology. Glycans on their own can be therapeutic targets as well as being biocompatible and nontoxic carriers in nanoparticle (NP) platforms to deliver therapeutical agents to biological targets.. Nanoscale multimeric glycans such as glycoliposomes, glycopolymers, and glycodendrimers are being fully exploited as new-generation phramaceuticals. Glycoinhibitors of enzymes involved in lysosomal storage diseases also constitute therapeutic targets of great value.
Carbohydrates, with their stereochemical richness and varied functionalities, are considered valuable for the treatment of bacterial and viral infections and constitute potent glycopharmaceutics. The recent development of glycan microarrays has also been a determinant for the more subtle identification of cancer markers and better selection of anticarbohydrate antibodies and lectins. Antibody–drug conjugates (ADCs) are of therapeutic importance provided that their glycans are properly engineered.
Editors:
Dr. Leila Mousavifar
Research Advisor, Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, QC H3C 3P8, Canada
Prof. Dr. René Roy
Department of Chemistry, Université du Quebéc à Montréal, P.O. Box 8888, Succ. Centre-Ville, Montreal, QC H3C 3P8, Canada
Deadline for manuscript submissions: 20 May 2023
The link to the Special Issue Website:
https://www.mdpi.com/journal/pharmaceutics/special_issues/L22Q6SQVME