Tis Special Issue is for the journal Pharmaceutics (ISSN 1999-4923; Impact Factor: 6.525).
Orally disintegrating delivery systems (ODDSs) are pharmaceutical forms designed to rapidly disintegrate or dissolve in the oral cavity without using water. Tablets, capsules, films, patches, strips, wafers, granules, micro and nano systems or others aimed both for a local and systemic action can improve the onset of action and the compliance in children or patients with swallowing challenges. On the other hand, a low drug solubility can be a problem for an OD dosage form, not only for palatability reduction but also for drug bioavailability. Cyclodextrins (CDs) are cyclic oligosaccharides, widely used as safe pharmaceutical excipients, and are able to improve drug bioavailability, stability and acceptability by forming inclusion complexes in aqueous solutions. Moreover, cyclodextrin properties can be exploited to improve ODD disintegration. This Special Issue serves to highlight the application of cyclodextrins in ODDs. We invite articles on all pharmaceutical dosage forms of CDs-based ODDs for this Special Issue.
Guest Editor: Dr. Francesca Maestrelli
Department of Chemistry “U. Schiff”, University of Florence, Via Schiff 6, Sesto Fiorentino, 50019 Florence, Italy
Deadline for manuscript submissions: 15 December 2022