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Tag: senescence

June 9, 2025 CD as API / Food / Pharma applications

Gut microbiota-dependent increase in phenylacetic acid induces endothelial cell senescence during aging

With advanced age, alterations of specific gut-derived metabolites such as aromatic amino acid derivatives might contribute to CVD through prolonged

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April 14, 2025 Life sciences

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD

The association between cellular senescence and ABCA1 expression in human postmortem brain samples was studied using transcriptomic, histological, and biochemical

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March 13, 2025 CD as API / Pharma applications / Uncategorized

CD treatment against cellular senescence

Cellular senescence, a hallmark of aging, has been implicated in Alzheimer’s disease (AD) pathogenesis. Cholesterol accumulation is known to drive

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