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Tag: SARS-CoV-2

May 13, 2022 Drug delivery / Pharma applications

Buccal administration of remdesivir – still far from reality

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,

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April 11, 2022 Drug delivery / Pharma applications

Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir

The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of

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February 3, 2022 Drug delivery / Pharma applications

Scientists are racing to develop more COVID antivirals

Nature News evaluated antiviral drugs developed for the treatment of Covid-19. Clinical-trial data showed that molnupiravir, developed by the pharmaceutical

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December 22, 2021 CD as API / Pharma applications

Alpha-cyclodextrin and Hydroxytyrosol against SARS-CoV-2 infection

In the last year, the Cyclodextrin News reported on an oral spray containing alpha-cyclodextrin and hydroxytyrosol developed by Italian researchers

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October 1, 2021 Drug delivery / Pharma applications

Memorial Sloan Kettering Cancer Center: Potential treatment of COVID-19 using inhalable camostat/nafamostat formulated with HPBCD or SBECD

Memorial Sloan Kettering Cancer Center (MSKCC) has filed a patent application on an inhalational therapeutic composition of camostat solubilized by

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syringe and pills on blue background
September 17, 2021 CD derivatives / Drug delivery

Harvard scientists discover the prophylactic effect of SBECD solubilized amodiaquine against SARS-CoV2 infection

Amodiaquine is a commonly used medicament for the treatment of malarial infections. It is a 4-aminoquinoline compound similar to chloroquine

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June 30, 2021 CD as API / Pharma applications

Recent reviews on cyclodextrins against SARS-CoV-2

Recent reviews emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2. Cholesterol-rich parts of cell membranes serve

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June 1, 2021 Drug delivery / Pharma applications

A combinatory treatment of Hepatitis C drugs with Remdesivir show strong effectiveness against COVID-19

Science News reported that a combination of remdesivir, a drug formulated by SBECD and currently approved in the United States

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March 16, 2021 Drug delivery / Pharma applications

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

Drug combination strategies of repurposed drugs offer a number of advantages to monotherapies including the potential to achieve greater efficacy,

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March 4, 2021 Drug delivery / Pharma applications

FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine

As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen

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  • Recent important review articles from Thorsteinn Loftsson's group about ophthalmic drug delivery
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  • CIDALTEX® ANTIVIRAL MASKS DURING THE COVID-19 PANDEMIC
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Matthieu SOLLOGOUB at ICS 20
  • GRAS status of CD derivatives
  • Mallinckrodt gave up further development of adrabetadex (VTS-270; HPBCD)
  • Application of cyclodextrin containing sliding-ring polymers in oil-well cement
  • Egg-Free Bakery - Recommendation from Wacker

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