Buccal administration of remdesivir – still far from reality
As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,
Tag: SARS-CoV-2
Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir
The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of
Scientists are racing to develop more COVID antivirals
Nature News evaluated antiviral drugs developed for the treatment of Covid-19. Clinical-trial data showed that molnupiravir, developed by the pharmaceutical
Alpha-cyclodextrin and Hydroxytyrosol against SARS-CoV-2 infection
In the last year, the Cyclodextrin News reported on an oral spray containing alpha-cyclodextrin and hydroxytyrosol developed by Italian researchers
Memorial Sloan Kettering Cancer Center: Potential treatment of COVID-19 using inhalable camostat/nafamostat formulated with HPBCD or SBECD
Memorial Sloan Kettering Cancer Center (MSKCC) has filed a patent application on an inhalational therapeutic composition of camostat solubilized by
Harvard scientists discover the prophylactic effect of SBECD solubilized amodiaquine against SARS-CoV2 infection
Amodiaquine is a commonly used medicament for the treatment of malarial infections. It is a 4-aminoquinoline compound similar to chloroquine
Recent reviews on cyclodextrins against SARS-CoV-2
Recent reviews emphasized the role of membrane lipids in the infectivity mechanism of SARS-COV-2. Cholesterol-rich parts of cell membranes serve
A combinatory treatment of Hepatitis C drugs with Remdesivir show strong effectiveness against COVID-19
Science News reported that a combination of remdesivir, a drug formulated by SBECD and currently approved in the United States
Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2
Drug combination strategies of repurposed drugs offer a number of advantages to monotherapies including the potential to achieve greater efficacy,
FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine
As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen