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Tag: SARS-CoV-2

December 19, 2022 CD as API / Pharma applications

HPβ-CD as affordable antiviral to treat coronavirus infection

In a recent study posted to the bioRxiv* preprint server, researchers identified β-cyclodextrins (β-CDs) as a safe and cost-effective drug

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November 3, 2022 Drug delivery / Pharma applications

Molecular docking assisted exploration on solubilization of poorly soluble drug remdesivir in sulfobutyl ether-beta-cyclodextrin: stabilization of supersaturated solution by changing pH from 1.7 to 3.5

In terms of solubilization effect, it was found that phase solubility of RDV increased significantly from intrinsic 1.7 mmol/L at

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October 28, 2022 Drug delivery / Pharma applications

Impact of Remdesivir on SARS-CoV-2 Clearance in a Real-Life Setting: A Matched-Cohort Study

There were 648 patients enrolled in the study (216 cases and 432 controls). Viral clearance (VC) was observed in 490

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September 5, 2022 CD as API / Pharma applications

HPBCD inhibits SARS-CoV-2 replication and virus-induced inflammatory cytokines

COVID-19 is marked by extensive damage to the respiratory system, often accompanied by systemic manifestations, due to both viral cytopathic

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May 13, 2022 Drug delivery / Pharma applications

Buccal administration of remdesivir – still far from reality

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,

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April 11, 2022 Drug delivery / Pharma applications

Use of Antivirals in SARS-CoV-2 Infection. Critical Review of the Role of Remdesivir

The aim of this report is to review the literature and shed light on the uncertainties surrounding the use of

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February 3, 2022 Drug delivery / Pharma applications

Scientists are racing to develop more COVID antivirals

Nature News evaluated antiviral drugs developed for the treatment of Covid-19. Clinical-trial data showed that molnupiravir, developed by the pharmaceutical

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December 22, 2021 CD as API / Pharma applications

Alpha-cyclodextrin and Hydroxytyrosol against SARS-CoV-2 infection

In the last year, the Cyclodextrin News reported on an oral spray containing alpha-cyclodextrin and hydroxytyrosol developed by Italian researchers

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October 1, 2021 Drug delivery / Pharma applications

Memorial Sloan Kettering Cancer Center: Potential treatment of COVID-19 using inhalable camostat/nafamostat formulated with HPBCD or SBECD

Memorial Sloan Kettering Cancer Center (MSKCC) has filed a patent application on an inhalational therapeutic composition of camostat solubilized by

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syringe and pills on blue background
September 17, 2021 CD derivatives / Drug delivery

Harvard scientists discover the prophylactic effect of SBECD solubilized amodiaquine against SARS-CoV2 infection

Amodiaquine is a commonly used medicament for the treatment of malarial infections. It is a 4-aminoquinoline compound similar to chloroquine

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  • γ-Cyclodextrin/Epigallocatechin-3-gallate Inclusion Complexes as Efficient Antioxidants for Preservation of Shrimp Surimi Products
  • Small anticancer drug release by light
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