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Tag: pharmacokinetics

February 26, 2026 CD derivatives / Drug delivery / Pharma applications

Cyclodextrin Polymer Complexation Improves the Tolerability of Parenteral Oestradiol

This study investigates the PEG‑β‑CD polymer, a water‑soluble polyethylene glycol–β‑cyclodextrin cross‑linked carrier, as a potential alternative to conventional oestradiol formulations

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February 5, 2024 Drug delivery / Pharma applications

Do Polymeric Nanoparticles Really Enhance the Bioavailability of Oral Drugs? A Quantitative Answer Using Meta-Analysis

The oral route remains one of the most popular and important routes of administration for drugs—one that warrants the development

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October 26, 2022 Drug delivery / Pharma applications

Pharmacokinetic study of sulfobutylether beta-cyclodextrin as an excipient of remdesivir

SBECD (Captisol®) with an average degree of substitution of 6.5 sulfobutylether functional groups (SBE = 6.5), is a solubility enhancer

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May 13, 2022 Drug delivery / Pharma applications

Buccal administration of remdesivir – still far from reality

As remdesivir, the first FDA-approved drug for SARS-CoV-2 infection, can be used only for hospitalized patients due to intravenous administration,

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March 10, 2022 Drug delivery / Pharma applications

The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats

 In this study, understanding the in vivo fate of β-cyclodextrin, a LC-MS/MS method was developed to facilitate simultaneous quantitative analysis

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Recent Posts

  • 4th International Aquatic Biotechnology Symposium
  • Cyclodextrin metal-organic framework engineered titanium surface: Targeted modulation of foam cell lipid homeostasis and inflammatory resolution
  • Reviewing Cyclodextrin-Grafted Polysaccharides as Sustainable Platforms for Biomedical and Environmental Applications
  • Complexation of Citalopram with β-Cyclodextrin, Mono-Subetadex and Subetadex – A Comparison of Analytical Techniques
  • Effect of cyclodextrins on cardiometabolic indices: a systematic review and meta-analysis of randomized controlled trials

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Top Posts

  • Reviewing Cyclodextrin-Grafted Polysaccharides as Sustainable Platforms for Biomedical and Environmental Applications
  • 4th International Aquatic Biotechnology Symposium
  • FDA: Inclusion complex of a GRAS guest and a GRAS host is also GRAS
  • Are cyclodextrins safe for intravitreal injections?
  • Cyclodextrin metal-organic framework engineered titanium surface: Targeted modulation of foam cell lipid homeostasis and inflammatory resolution
  • Complexation of Citalopram with β-Cyclodextrin, Mono-Subetadex and Subetadex - A Comparison of Analytical Techniques
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Antibody conjugated cyclodextrin for tumor drug delivery
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • Impact of Cholesterol Depletion by Methyl BCD on Dopamine Transmission Dynamics in Brain

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