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July 18, 2025 Drug delivery / Pharma applications

Hypoxia-responsive core-cross-linked supramolecular nanoprodrug based on dendritic drug-drug conjugates for synergetic anticancer therapy

A hypoxia-responsive dendritic drug-drug conjugates IR806-(Azo-CB)4 was prepared and combined with β-cyclodextrin-pendant poly(ethylene glycol)-block-poly(glutamic acid) block copolymer (PEG-PGlu-CD) to construct

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  • Chitosan-coated cyclodextrin-based niosomes enable enhanced nose-to-brain delivery of rivastigmine and asiaticoside for Alzheimer's disease
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  • Combined cyclodextrins and porphyrinoid derivatives in drug delivery systems
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