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Tag: mitophagy

February 21, 2023 CD as API / Pharma applications

Parkinson’s Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment

Parkinson-disease-patient-derived cells presented differences in their energetic profile, imbalanced proliferation, apoptosis, mitophagy, and a reduced differentiation efficiency to tyrosine hydroxylase

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February 23, 2022 CD as API / Pharma applications

HPBCD for Treatment of Parkinson Disease

The recent work of Jarazo et al. demonstrates that HP-β-CD ameliorates the dopaminergic neuronal loss phenotype, confirming the therapeutic potential

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November 23, 2021 CD as API / Pharma applications

Folate-appended CDs in cancer therapy

The team of Motoyama in Kumamoto has recently published new results on folate-appended CDs in leukemia and ovarian cancer (1,2).

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Top Posts

  • Events of American Cyclodextrin Consortium
  • Cyclarity Unveils First-Ever Clinical Data Demonstrating Excretion of Oxidized Cholesterol, at American Heart Association Vascular Discovery Scientific Sessions
  • Using cyclodextrin is not rocket science...except for NASA researchers.
  • FDA Grants Approval to HPBCD-Enhanced Biologic: A 'Super-Originator' Formulation
  • HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
  • Cyclodextrin dimers to treat atherosclerotic plaques by targeting various forms of cholesterol
  • Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins
  • HPaCD against Alzheimer Disease
  • Launch of KLEPTOSE® Crysmeb Methyl-Beta-Cyclodextrin for Oral and Parenteral Formulations
  • Global Summit on Pharmaceutical and Medicinal Chemistry (PMC2022)

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