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Tag: HPBCD

May 29, 2025 Drug delivery / Pharma applications

Theoretical Calculation of the Solubility and Other Parameters for Poorly Water-Soluble Compounds from Binding Constants of Inclusion Complexes

Experimental determination of solubility is a time-consuming procedure with relatively high reagent consumption. The solubility of poorly water-soluble compounds in

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May 27, 2025 CD as API / Drug delivery / Pharma applications

Global Cyclodextrins in Pharmaceutical Market Size

The global Cyclodextrins in Pharmaceutical Market market stood at USD 1.2 billion in 2024 and is forecasted to achieve USD

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May 20, 2025 Drug delivery / Pharma applications

Improved Bioavailability of Alpha-Lipoic Acid Through Cyclodextrin Complexation: A Potential for Enhanced Obesity Treatment

Alpha-lipoic acid (ALA) demonstrates significant therapeutic potential in obesity treatment and associated comorbidities, including diabetic neuropathy and hyperlipidemia. However, effective

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Lungs, anatomy hand drawn illustration
May 19, 2025 CD as API / Drug delivery / Pharma applications

Cyclodextrin-based materials for pulmonary delivery: Insights and challenges

The literature provides a large range of information on the manufacturing of CD-based materials for pulmonary delivery, the characterization of

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May 16, 2025 Drug delivery / Pharma applications / Uncategorized

SBECD, HPBCD and hydrophilic polymers to enhance the solubility of Benzthiazide, Isoxicam, and Piroxicam

The bioavailability of a drug depends, among other parameters, on solubility. One of the strategies used to enhance the solubility

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May 14, 2025 Drug delivery / Pharma applications / Uncategorized

Caffeine–Hydroxypropyl-β-Cyclodextrin Complex for Skin Treatment

Caffeine is a well-known xanthine that possesses antioxidant effects that could contribute to its application in different skin disorders. In

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May 12, 2025 CD as API / Drug delivery / Uncategorized

Cyclodextrin Complexes: A New Hope Against Atherosclerosis

Recently, increasing evidence shows that cyclodextrins have an inhibitory effect against atherosclerosis, a chronic disease inducing atherosclerotic cardiovascular diseases (ASCVDs).

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a man holding his tummy
May 8, 2025 CD derivatives / Drug delivery / Pharma applications

FDA Grants Approval to HPBCD-Enhanced Biologic: A ‘Super-Originator’ Formulation

Cyclodextrin-based super-generics represent enhanced versions of reformulated drug products, offering improved performance and patient outcomes usually developed/marketed by a generic

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April 28, 2025 Drug delivery / Pharma applications

Recent studies on dimethyl beta-CD

DIMEB (heptakis(2,6-di-O-methyl)-β-cyclodextrin, DMβCD (CYL-4668), was used for improving the solubility of Olmesartan medoxomil (OLM), the prodrug of olmesartan, an angiotensin II

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medications lying on table by ill woman on sofa
April 15, 2025 Drug delivery / Pharma applications

45 years of paracetamol (acetaminophen)–beta-cyclodextrin complex history – now used in versatile pharmaceuticals

According to the Cyclodextrin News Library Database, the first description of the paracetamol (acetaminophen)–beta-cyclodextrin complex, published in 1980, is partly

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Recent Posts

  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • Paul Janssen was born 100 years ago
  • Adsorption of PFAS to Cationic β-Cyclodextrin Polymers
  • A cyclodextrin polymer that could change the future of batteries
  • Virus-Mediated Self-Assembly of Functional Cyclodextrins for Antiviral Inhibition

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Top Posts

  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • BCD in starch-based composite active sheets for the preservation and packaging of blueberry fresh fruit
  • Reinforced double-threaded slide-ring networks for accelerated hydrogel discovery and 3D printing
  • Cyclodextrin scientist ranked among the Best Chemistry Scientists of the World
  • Adsorption of PFAS to Cationic β-Cyclodextrin Polymers
  • Paul Janssen was born 100 years ago
  • Cothreading of Unmodified and Monoazidated β-Mixed cyclodextrins in polyrotaxanes for Niemann Pick disease
  • Alpha-cyclodextrin increases glucagon-like peptide-1 secretion in multiple models and improves metabolic status in mice
  • Wasabi's bioactive component 6-MSITC formulated with alfa-cyclodextrin improved memory proven in clinical trial.
  • Bridion® injection now approved for patients of all ages

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