HPαCD Therapy: A Breakthrough for Krabbe Disease Treatment
Several North-American Universities worked together to find hydroxzpropyl-alpha-cyclodextrin(HPaCD) for the treatment of Krabbe disease. The deficiency of β-galactosylceramidase causes a
Tag: HPACD
The Effect of Cyclodextrins in Cholesterol and Ganglioside Depletion in Rat Brain Synaptosomes
In this recently published article, the effect of four cyclodextrin derivatives on cholesterol and ganglioside depletion was investigated: two alpha
HPaCD against Alzheimer Disease
HP-beta-cyclodextrin (HPbCD) is currently in clinical trials against Niemann-Pick Disease Type C (NPC) and Alzheimer’s Disease (AD) and these trials
Alpha-cyclodextrin and Hydroxytyrosol against SARS-CoV-2 infection
In the last year, the Cyclodextrin News reported on an oral spray containing alpha-cyclodextrin and hydroxytyrosol developed by Italian researchers
Use of cyclodextrins in diseases and disorders involving phospholipid dysregulation
A patent application by Knut M. Wittkowski (ASDERA LLC, US) entitled “Use of cyclodextrins in diseases and disorders involving phospholipid
Different cyclodextrins to treat NPC
If you are following advances in the re-discovery of cyclodextrins as APIs, there is quite a race among the candidates