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Tag: degree of substitution

May 6, 2024 Non-pharma applications / Pharma applications

Cyclodextrins: Establishing building blocks for AI-driven drug design by determining affinity constants in silico

The effectiveness of cyclodextrins depends on their ability to encapsulate target molecules with strong affinity and specificity, but quantifying affinities

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January 25, 2024 CD derivatives

Counteracting Influence of 2-hydroxypropyl Substitution and the Presence of Guest on the Shape and Size of β-Cyclodextrin Cavity

The aqueous solubility of the β-Cyclodextrin (βCD), a cyclic carbohydrate comprising seven α-D-glucose molecules, is enhanced by 2-hydroxypropyl (2-HP) substitution

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December 21, 2023 Pharma applications

Nanalysis Benchtop NMR with USP Monographs and Betadex

Following our recent publication “Molar Substitution Determination in Hydroxypropyl Betadex According to USP-NF/Ph. Eur. (1804) Monograph Method Using 1H Benchtop

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June 16, 2021 CD derivatives / Drug delivery / Pharma applications

European Patent Office upholds Curadev’s SBE-β-CD patent for new composition of matter

Yahoo Finance published: Working with Professor Steve Wicks and his team at the University of Greenwich, Curadev developed a new method for

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September 6, 2018 E-ducation / Non-pharma applications / Pharma applications

Video-class on History of Cyclodextrins

Starting from the discovery of cyclodextrins (“cellulosines” at that time) by Villiers in 1891 the history of cyclodextrin research is

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Recent Posts

  • Thermodynamic and Molecular Modeling Study of the Veratric Aldehyde/β-Cyclodextrin Inclusion Complex and Its Inhibitory Effect on Polyphenoloxidase
  • Pufferfish (fugu) sushi wih CD-stabilized sauce
  • Self-assembly of Cationic Permethylated Cyclodextrins
  • Cationic Cyclodextrin-Based Carriers for Drug and Nucleic Acid Delivery
  • Special issue: “Synthesis, Analysis and Applications of Cyclodextrins and Their Derivatives”

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Top Posts

  • Thermodynamic and Molecular Modeling Study of the Veratric Aldehyde/β-Cyclodextrin Inclusion Complex and Its Inhibitory Effect on Polyphenoloxidase
  • MIT scientists filed patent for HPBCD treatment in Alzheimer's disease
  • Lanosterol eye drops for cataract treatment
  • New FDA approved medicinal product containing Betadex sulfobutylether sodium: VYKOURA
  • Pufferfish (fugu) sushi wih CD-stabilized sauce
  • Carbohydrate drugs (Part 5) (Oligosaccharides, cyclodextrins)
  • GRAS status of CD derivatives
  • Aqueous eye drop formulations: Cyclodextrins as enabling excipients
  • Comparative evaluation of lyophilized voriconazole formulations marketed in European Union
  • Self-assembly of Cationic Permethylated Cyclodextrins

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