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Tag: Covid-19

April 16, 2021 Drug delivery / Pharma applications

Sulfobutylether-beta-cyclodextrin-enabled antiviral remdesivir: characterization of electrospun- and lyophilized formulations

Veklury™ by Gilead Sciences, Inc., containing antiviral drug, remdesivir (REM) has received emergency authorization in the USA and in Europe

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April 1, 2021 Drug delivery / Pharma applications

Reduced mortality rate and shorter time for clinical improvement upon Remdesivir treatment

This retrospective comparative effectiveness research study was conducted from March 4 to August 29, 2020, in a 5-hospital health system

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March 24, 2021 CD as API / Drug delivery / Pharma applications

Meet the Experts: Applications of Cyclodextrins in the Pharma Industries

A webinar organized by CycloLab will be held on April 15-16, 2021. Participation at the event is provided free of charge

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March 16, 2021 Drug delivery / Pharma applications

Remdesivir-Ivermectin combination displays synergistic interaction with improved in vitro antiviral activity against SARS-CoV-2

Drug combination strategies of repurposed drugs offer a number of advantages to monotherapies including the potential to achieve greater efficacy,

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March 12, 2021 Drug delivery / Pharma applications

An interesting hypothesis: CD‐sACE2 inclusion compounds to treat COVID‐19

Angiotensin‐converting enzyme 2 (ACE2) has been identified as the main receptors for SARS‐CoV and SARS‐CoV‐2. Soluble ACE2 (sACE2) can bind

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March 4, 2021 Drug delivery / Pharma applications

FDA Issues Emergency Use Authorization for Third COVID-19 Vaccine

As we reported on CDN blog FDA approval for Janssen vaccine containing HPBCD was expected in late February. The Janssen

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person holding syringe
February 25, 2021 CD derivatives / Pharma applications

HPBCD is a unique component in Janssen’s COVID-19 vaccine candidate

Amongst Janssen’s novel single-dose Covid-19 vaccine candidate of adenovirus platform excipients one might notice a peculiar compound: Hydroxypropyl Betadex (HPBCD).

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February 19, 2021 Drug delivery / Pharma applications / Uncategorized

NIH funds study to evaluate remdesivir for COVID-19 in pregnancy

A new study funded by the National Institutes of Health will evaluate the effects of remdesivir in pregnant women who

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February 15, 2021 Drug delivery / Pharma applications

Reviews on remdesivir in Covid-19 treatment

Remdesivir (GS-5734; Gilead Sciences Inc., US) is an investigational nucleoside analog that acts as a competitive inhibitor of viral RNAdependent

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February 10, 2021 Drug delivery / Pharma applications

RotaChrom Technologies Partners With Cyclolab to Increase Production of COVID-19 Treatment

RotaChrom Technologies, the developer of the world’s first industrial-scale Centrifugal Partition Chromatography (CPC) technology platform, announced today the launch of

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Recent Posts

  • Concluding 22nd International Cyclodextrin Symposium (ICS-22)
  • Enhancing Linezolid Solubilization with β-Cyclodextrin Polymer Fractions of Different Molecula Weight
  • Book chapter: Functionalized cyclodextrins in drug delivery
  • β-Cyclodextrin-Complexed 1,8-Cineole Attenuates Motor Deficits and Preserves Tyrosine Hydroxylase Immunoreactivity in a Reserpine-Induced Mouse Model of Parkinsonism
  • Disruption of endosomal transport in cyclodextrin-mediated cytotoxicity

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Top Posts

  • Enhancing Linezolid Solubilization with β-Cyclodextrin Polymer Fractions of Different Molecula Weight
  • Rafael Holdings Announced Submission of New Drug Application to FDA for Trappsol®Cyclo™ (remibetadex) for the Treatment of Niemann-Pick Disease Type C
  • Concluding 22nd International Cyclodextrin Symposium (ICS-22)
  • Cyclodextrin Produced In situ: Rethinking Oat Milk Design for Better Performance
  • Disruption of endosomal transport in cyclodextrin-mediated cytotoxicity
  • Practical Considerations about the Cyclodextrin Solubilities – A Quickstart Guide for Newbies
  • Arthur Lütringhaus, Godfather of catenanes was born 120 years ago
  • 16th Central European Symposium on Pharmaceutical Technology (CESPT 2027)
  • β-Cyclodextrin-Complexed 1,8-Cineole Attenuates Motor Deficits and Preserves Tyrosine Hydroxylase Immunoreactivity in a Reserpine-Induced Mouse Model of Parkinsonism
  • Enantioseparation and molecular docking study of selected chiral pharmaceuticals on a commercialized phenylcarbamate-β-cyclodextrin column using polar organic mode

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